Transgenic Animals Video Lecture - NEET

transgenic animals we're here to talk
about how they're made you're probably
curious
solty to what they're all about
so we'll teach you a down
so what is a transgenic animal a
transgenic animal is one whose genome
has been deliberately altered by the
transfer of a gene or genes from another
species or breed the most common way of
creating transgenic animals is there DNA
microinjection in this example we'll be
inserting a human gene into a cow the
human gene is micro injected into the
egg from the egg donor this egg will be
reinserted and developed in the host cow
to become the transgenic cow the
transgenic cow will express the human
gene in one form or another in this case
in the milk
to clone a transgenic animal to a nuclei
from the adult transgenic cow cells are
micro injected and enucleated eggs
provided from the egg donor
these new eggs will then be developed in
the host cow to eventually become clone
transgenic cows these cows should also
express the gene that was expressed in
the original transgenic cow
now let's take a look at how DNA is
cloned here we have a human cell and a
bacterium human DNA will be isolated as
well as a plasmid from the bacterium
next restriction enzymes will cut the
human DNA to isolate the human insulin
gene and will also cleave the plasmid
leaving sticky end to the gene will
recognize then DNA ligase joins a gene
and plasma together to create the
recombinant DNA
the recombinant DNA will develop in the
host cell and DNA cloning will occur
transgenic animals they're kind of crazy
to think about and we gotta talk about
the ethics and the pros and cons the
ethics and the process
those who are for transgenesis argues
with the basis of utilitarianism meaning
that the best moral action is one that
maximizes utility for example if we were
to do an experiment on a cow one that
might harm the cow if it Altima Tring
spa's ative results for many more of
another species such as humans then it
outweighs the harm that we are doing to
the cow another argument for those who
are for transgenesis is increased our
cultural efficiency which means that
there is a higher ratio of agricultural
outputs to agricultural inputs which can
also be applied with the aim of reducing
our cultural pollution for example the
enviro pig the enviro pig has been
genetically modified to produce an
enzyme that breaks down dietary
phosphorus limiting the amount of
phosphorus released in its poop animals
may also become genetically modified to
be disease resistant allowing for better
management of them examples include
immunity being conferred to the
offspring the antibody expression in the
milk of the mother and parasite control
and sheep and goats
another Pro for transgenic animals is
it's possible benefits to human health
for example pigs have been genetically
engineered for higher levels of omega-3
clothing may be useful to help
endangered species this technology could
be applied to either extinct or
endangered species cloning may help
retain genetic diversity and small
populations of endangered organisms and
ultimately in our world
one of the most significant uses of
transgenic animals is when it comes to
understanding diseases and drug
discovery animal models of human disease
are valuable resources for understanding
how and why a particular disease
develops and what can be done to halt or
reverse the process the use of
genetically engineered animals has also
become routine within the pharmaceutical
industry for drug discovery drug
development and risk assessment
animal rights is a foundation of those
who are against chance Genesis and
against animal testing in general
manipulating animals for human ends as
if the animal were nothing more than
human property is inhumane transgenic ly
producing animals could have a range of
unexpected side effects and will harm
the well-being of animals in
unpredictable ways some also argue that
humans are playing God individuals have
argued that crossing species boundaries
is unnatural immoral and in violation of
God's laws another argument against
transgenesis
is the threat it poses to the natural
system of society the International
Olympic Committee has expressed concern
that athletes will soon employ genetic
engineering to get an edge if
individuals are willing to genetically
manipulate their children to make them
better athletes and it's likely that
individuals will be willing to
manipulate their children to be more
intelligent or whatever the parents
think would give them an advantage
transgenic animals they glow in the dark
in there