Drug | Medical Science Optional Notes for UPSC PDF Download

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Drug | Medical Science Optional Notes for UPSC

Drug | Medical Science Optional Notes for UPSC

Reflex tachycardia resulting from vasodilation and compensatory mechanisms leading to sodium and fluid retention is a common occurrence with all vasodilators. Optimal usage involves their combination with diuretics and beta blockers. The primary adverse effects associated with vasodilators include tachycardia and headaches. This encompasses calcium channel blockers, potassium channel blockers, and NO releasing agents.

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Drug | Medical Science Optional Notes for UPSC

Drug | Medical Science Optional Notes for UPSCDrug | Medical Science Optional Notes for UPSC

Nitrates are exclusively used in Management of Angina

Drug | Medical Science Optional Notes for UPSC

Drug | Medical Science Optional Notes for UPSCDrug | Medical Science Optional Notes for UPSC

The document Drug | Medical Science Optional Notes for UPSC is a part of the UPSC Course Medical Science Optional Notes for UPSC.
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1. What are nitrates used for in the management of angina?
Ans. Nitrates are exclusively used in the management of angina, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart. Nitrates help to relax and widen the blood vessels, improving blood flow to the heart and relieving angina symptoms.
2. How do nitrates work in the body to manage angina?
Ans. Nitrates work by releasing nitric oxide, which is a potent vasodilator. Nitric oxide relaxes the smooth muscles in the blood vessels, leading to their dilation. As a result, the blood vessels widen, allowing increased blood flow to the heart. This increased blood flow helps to relieve angina symptoms.
3. What are the different forms of nitrates available for angina management?
Ans. Nitrates for angina management are available in various forms, such as sublingual tablets, sprays, patches, and extended-release capsules or tablets. Sublingual tablets and sprays are commonly used for immediate relief of angina symptoms, while patches and extended-release formulations provide a more sustained effect.
4. What are the possible side effects of nitrates used in angina management?
Ans. Nitrates can cause certain side effects, although they are usually mild and transient. Common side effects may include headaches, dizziness, flushing, and low blood pressure. In some cases, nitrates may also cause reflex tachycardia (increased heart rate) or tolerance, where the effectiveness of the medication decreases over time.
5. Can nitrates be used by everyone with angina?
Ans. Nitrates are generally safe and effective for most individuals with angina. However, they may not be suitable for everyone. Individuals with certain medical conditions, such as severe anemia, hypotension, or glaucoma, may need to exercise caution or avoid nitrates altogether. It is important to consult a healthcare professional to determine the appropriateness of nitrates for individual cases.
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