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All questions of Biomolecules for NEET Exam

The cell membranes are mainly composed of        [2005]
  • a)
    fats
  • b)
    proteins
  • c)
    phospholipids
  • d)
    carbohydrates
Correct answer is option 'C'. Can you explain this answer?

Muskaan Basak answered
Cell membranes (Plasma membranes) constitutes bilayer of phospholipid with embedded proteins. In humans, lipids accounts for upto 79% of cell membrance.

Phospholipids are esters of glycerol with         [2003]
  • a)
    Three phosphate groups
  • b)
    Three carboxylic acid residues
  • c)
    Two carboxylic acid residues and onephosphate group
  • d)
    One carboxylic acid residue and twophosphate groups
Correct answer is option 'C'. Can you explain this answer?

Phospholipids are derivatives of glycerol in
which two of the hydroxyl groups are
esterified with fatty acids while the third is
esterified with some derivative of phosphoric
acid with some alcohol such as choline,
ethanolamine, serine or inositol.

Cellulose is a polymer of         [2002]
  • a)
    Glucose
  • b)
    Fructose
  • c)
    Ribose
  • d)
    Sucrose
Correct answer is option 'A'. Can you explain this answer?

Yash Saha answered
We know that cellulose (C6H12O6 )n is the
chief constituent of cell walls of plants. It is
the most abundant organic substance found
in nature. It is a polymer of glucose with
3500 repeat units in a chain.

RNA and DNA are chiral molecules, their chiralityis due to [2007]
  • a)
    chiral bases
  • b)
    chiral phosphate ester units
  • c)
    D-sugar component
  • d)
    L-sugar component.
Correct answer is option 'C'. Can you explain this answer?

Arindam Khanna answered
Each nucleic acid consists of a pentose
sugar a heterocyclic base, and phosphoric
acid. The sugar present in DNA is 2-deoxy
-D (–) ribose and the sugar present in RNA
is D (–)- ribose. The chirality of DNA and
RNA molecules are due to the presence of
sugar components.

The helical structure of protein is stabilized by        [2004]
  • a)
    dipeptide bonds
  • b)
    hydrogen bonds
  • c)
    ether bonds
  • d)
    peptide bonds
Correct answer is option 'B'. Can you explain this answer?

Nabanita Basu answered
Stabilization of Helical Structure in Proteins
The helical structure of proteins is a fundamental aspect of their secondary structure, primarily found in alpha helices. This structure is crucial for the overall shape and function of proteins.
Role of Hydrogen Bonds
- Hydrogen bonds play a vital role in stabilizing the helical structure of proteins.
- In an alpha helix, the carbonyl oxygen (C=O) of one amino acid forms a hydrogen bond with the amide hydrogen (N-H) of another amino acid located four residues down the chain.
- These hydrogen bonds create a regular pattern that promotes the coiling of the polypeptide chain into a helical formation.
Importance of Hydrogen Bonding
- The consistent formation of hydrogen bonds along the length of the helix gives it stability and makes it resilient to environmental changes.
- Hydrogen bonds are relatively weak compared to covalent bonds, but their cumulative effect in a long helix can provide significant structural integrity.
- This stabilization is crucial for the protein's overall folding and functional conformation.
Other Bonds in Proteins
- While dipeptide bonds and peptide bonds are essential for linking amino acids together to form proteins, they do not contribute to the helical structure itself.
- Ether bonds are not typically found in proteins and do not have a role in stabilizing protein structures.
Conclusion
In summary, the helical structure of proteins is primarily stabilized by hydrogen bonds, which enable the formation of alpha helices, essential for the protein's stability and functionality.

Which of the statements about "Denaturation" given below are correct ?        [2011 M]

(a) Denaturation of proteins causes loss of secondary and tertiary structures of the protein.

(b) Denturation leads to the conversion of double strand of DNA into single strand

(c) Denaturation affects primary strucrture which gets distorted
  • a)
    (b) and (c)
  • b)
    (a) and (c)
  • c)
    (a) and (b)
  • d)
    (a), (b) and (c)
Correct answer is option 'C'. Can you explain this answer?

Anu Bajaj answered
When the proteins are subjected to the
action of heat, mineral acids or alkali, the
water soluble form of globular protein
changes to water insoluble fibrous protein.
This is called denaturation of proteins.
During denaturation secondary and tertiary
structures of protein destroyed but primary
structures remains intact.

A sequence of how many nucleotides inmessenger RNA makes a codon for an amino acid?   [2004]
  • a)
    Three
  • b)
    Four
  • c)
    One
  • d)
    Two
Correct answer is option 'A'. Can you explain this answer?

Krish Patel answered
The bond formed between two amino acids
by the elimination of a water molecule is
called a peptide linkage or bond. The peptide
bond is simply another name for amide bond.
The product formed by linking amino acid
molecules through peptide linkages. —
CO—NH—, is called a peptide

Which functional group participates indisulphide bond formation in proteins?      [2005]
  • a)
    Thioester
  • b)
    Thioether
  • c)
    Thiol
  • d)
    Thiolactone
Correct answer is option 'C'. Can you explain this answer?


Thiol group participates in disulphide bond formation in proteins

Disulphide bonds play a crucial role in stabilizing the tertiary structure of proteins by covalently linking different parts of the polypeptide chain. The formation of disulphide bonds involves the oxidation of two thiol groups (-SH) to form a covalent bond between the sulfur atoms.

Thiol group
- Thiol group, also known as sulfhydryl group, is a functional group containing a sulfur atom bonded to a hydrogen atom.
- In proteins, cysteine residues contain thiol groups that can participate in disulphide bond formation.

Disulphide bond formation
- The process of disulphide bond formation involves the oxidation of two thiol groups to form a covalent bond between the sulfur atoms.
- This process is often catalyzed by enzymes known as disulphide bond isomerases.

Importance of disulphide bonds
- Disulphide bonds play a crucial role in stabilizing the tertiary structure of proteins.
- They can help maintain the structural integrity of proteins in various environments.

In conclusion, the thiol group participates in disulphide bond formation in proteins by undergoing oxidation to form covalent bonds between sulfur atoms. This process is essential for maintaining the structural stability of proteins.

The human body does not produce       [2006]
  • a)
    Vitamins
  • b)
    Hormones
  • c)
    Enzymes
  • d)
    DNA
Correct answer is option 'A'. Can you explain this answer?

Ishani Nambiar answered
Vitamins are organic substances which does
not provide energy but are essential for
healthy growth and proper functioning of
body. Vitamins are not synthesized inside
human body but they are essential part of
our diet.

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