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All questions of Breathing and Exchange of Gases for NEET Exam

The inspiratory reserve volume + tidal volume + expiratory reserve volume is the same as
  • a)
    inspiratory capacity + expiratory reserve volume
  • b)
    total lung capacity − functional residual capacity
  • c)
    inspiratory capacity + functional residual capacity
  • d)
    inspiratory capacity + residual volume.
Correct answer is option 'A'. Can you explain this answer?

Vivek Patel answered
Inspiratory reserve volume (IRV) + tidal volume (TV) + expiratory reserve volume (ERV) represents vital capacity (VC). Now, inspiratory capacity is the total volume of ai that can be inhaled after a normal expiration. It includes tidal volume and inspiratory reserve volume i.e., IC = TV + IRV. Thus, option (a) is correct which says that vital capacity i.e., IRV + TV + ERV = IC + ERV.

Emphysema is a condition resulting from
  • a)
    cigarette smoking
  • b)
    liquor consumption
  • c)
    drug addiction
  • d)
    reduced oxygen carrying capacity of blood.
Correct answer is option 'A'. Can you explain this answer?

Gaurav Kumar answered
Emphysema is a respiratory disorder which occurs due to the inflation or abnormal distension of the bronchioles or alveolar sacs resulting in the loss of their elasticity. Cigarette smoking and chronic bronchitis are the causes of this disease.

Which one of the following is the correct statement for respiration in humans?
  • a)
    Cigarette smoking may lead to inflammation of bronchi.
  • b)
    Neural signals from pneumotaxic center in pons region of brain can increase the duration of inspiration.
  • c)
    About 90% of carbon dioxide is carried by haemoglobin as carbaminohaemoglobin.
  • d)
    Workers in grinding and stone-breaking industries may suffer from lung fibrosis.
Correct answer is option 'D'. Can you explain this answer?

Anjali Sharma answered
Grinding or stone breaking industries produce so mud dust that long exposure to this can give rise to inflammatior of lungs leading to fibrosis (proliferation of fibrous tissues' and thus causing serious lung damage. Inflammation ol the bronchi may also be caused by cigarette smoking. The primary function of pneumotaxic center is to limit inspiration which increase breathing rate.

Excessive cigarette smoking leading to damage of alveolar walls is associated with
  • a)
    Asthma
  • b)
    Emphysema
  • c)
    Silicosis
  • d)
    Botulism
Correct answer is option 'B'. Can you explain this answer?

Top Rankers answered
Excessive cigarette smoking leading to damage of alveolar walls is associated with emphysema. Emphysema is a type of chronic obstructive pulmonary disease (COPD) that is caused by damage to the air sacs (alveoli) in the lungs.
Topic in NCERT: DISORDERS OF RESPIRATORY SYSTEM
Line in NCERT: "Emphysema is a chronic disorder in which alveolar walls are damaged due to which respiratory surface is decreased. One of the major causes of this is cigarette smoking."

Given below are few respiratory disorders. Identify occupoational respiratory disorders among these.
(i) Coryza
(ii) SARS
(iii) Silicosis
(iv) Asbestosis
(v) Emphysema
  • a)
    (i)  and (ii)
  • b)
    (i) and (v)
  • c)
    (iii) and (iv)
  • d)
    (i), (ii) and (v)
Correct answer is option 'C'. Can you explain this answer?

Priya Menon answered
Silicosis and asbestosis are known as occupational disorder as they occur due to one's occuption. Workers working in industries where silica and asbestos are used can suffer from these respiratory disorders.

निम्नलिखित कथनों पर विचार करें:
1) कृषि मिट्टी पर्यावरण में नाइट्रोजन ऑक्साइड छोड़ती है।
2) मवेशी अमोनिया को पर्यावरण में छोड़ते हैं।
3) पोल्ट्री उद्योग पर्यावरण में प्रतिक्रियाशील नाइट्रोजन यौगिक जारी करता है।
ऊपर दिया गया कौन सा कथन सही है / हैं?
  • a)
    केवल 1 और 3
  • b)
    केवल 2 और 3
  • c)
    केवल 2
  • d)
    1, 2 और 3
Correct answer is option 'D'. Can you explain this answer?

Avi Sengupta answered
कृषि मिट्टी और नाइट्रोजन ऑक्साइड
- कृषि गतिविधियों से मिट्टी में मौजूद नाइट्रोजन ऑक्साइड का उत्सर्जन होता है। यह प्रक्रिया मुख्य रूप से उर्वरकों के उपयोग और विभिन्न कृषि तकनीकों के कारण होती है।
मवेशियों और अमोनिया
- मवेशियों का पाचन और मलत्याग प्रक्रिया अमोनिया का उत्सर्जन करती है। यह अमोनिया वायुमंडल में जाने के बाद पर्यावरण को प्रभावित करता है, जिससे प्रदूषण और स्वास्थ्य संबंधी समस्याएं हो सकती हैं।
पोल्ट्री उद्योग और प्रतिक्रियाशील नाइट्रोजन
- पोल्ट्री उद्योग भी प्रतिक्रियाशील नाइट्रोजन यौगिकों का उत्सर्जन करता है, जो कि पोल्ट्री खाद और अन्य अवशेषों से उत्पन्न होते हैं। ये यौगिक पर्यावरण में कई प्रकार की रासायनिक प्रतिक्रियाओं का कारण बनते हैं।
सारांश
- सभी तीन कथन सही हैं:
- कृषि मिट्टी से नाइट्रोजन ऑक्साइड का उत्सर्जन होता है।
- मवेशी अमोनिया छोड़ते हैं।
- पोल्ट्री उद्योग प्रतिक्रियाशील नाइट्रोजन यौगिक जारी करता है।
इसलिए, सही उत्तर 'D' है, जो सभी कथनों को सही मानता है।

Consider the following four statements and select the correct option stating which ones are true (T) and which ones are false (F).
(i) Expiration is normally brought about by the relaxation of inspiratory muscles.
(ii) Oxyhaemoglobin can hold much less carbon dioxide in the form of carbaminohaemoglobin than what deoxyhaemoglobin can.
(iii) A person can expel air the air from the lungs by a forceful expiration.
(iv) A rise in PCO2 increases the oxygen - affinity of haemoglobin.
  • a)
    (i) F, (ii) F, (iii) T, (iv) F
  • b)
    (i) T, (ii) T, (iii) F, (iv) F
  • c)
    (i) F, (ii) T, (iii) T, (iv) F
  • d)
    (i) T, (ii) T, (iii) T, (iv) F
Correct answer is option 'B'. Can you explain this answer?

Hansa Sharma answered
Expiration is normally brought about by the relaxation of inspiratory muscles. Oxyhaemoglobin can hold much less CO2 in the form of carbaminohemoglobin than what oxyhaemoglobin can. Aperson cannot expel all the air from the lungs even after forceful expiration. The collie of air which remains in the lungs after the most forceful expiration is called residual volume. It is about 1100 L to 1200 mL. A rise in pCO2 decrease the O2 affinity of hemoglobin.

During rest, the metabolic needs of the body are at their minimum. Which of the following is indicative of this situation?
  • a)
    Rate of breathing
  • b)
    O2 intake and CO2 output
  • c)
    Pulse rate
  • d)
    All of these
Correct answer is option 'D'. Can you explain this answer?

Anushka Ahuja answered
Answer:

During rest, the metabolic needs of the body are at their minimum. This means that the body requires less energy and therefore, the rate of various physiological processes is reduced. Several indicators can provide evidence of this situation, including the rate of breathing, O2 intake, CO2 output, and pulse rate.

Rate of Breathing:
During rest, the rate of breathing decreases. This is because the body's oxygen demand is lower and there is less need for the removal of carbon dioxide. The respiratory rate slows down, with each breath being deeper and more efficient. This helps conserve energy and maintain a balance between oxygen intake and carbon dioxide removal.

O2 Intake and CO2 Output:
During rest, the body's oxygen intake decreases as the metabolic rate decreases. The oxygen demand is lower, and therefore, the body requires less oxygen to support its functions. Similarly, the carbon dioxide output decreases as the metabolic rate decreases. This is because fewer metabolic processes are occurring, resulting in lower production of carbon dioxide as a waste product.

Pulse Rate:
During rest, the pulse rate tends to decrease. The heart does not need to pump blood as forcefully as during periods of physical activity. With the decrease in metabolic activity, the demand for oxygen and nutrients is reduced, resulting in a slower heart rate. This allows the heart to work more efficiently and conserve energy.

All of These:
The correct answer is option 'D' - all of these indicators (rate of breathing, O2 intake and CO2 output, and pulse rate) are indicative of the body's reduced metabolic needs during rest. These physiological changes occur to ensure that energy is conserved and the body functions optimally during periods of rest.

In summary, during rest, the body's metabolic needs are minimal, and various indicators such as the rate of breathing, O2 intake and CO2 output, and pulse rate reflect this situation. These changes help the body conserve energy and maintain a balanced physiological state during periods of rest.

Rate of breathing is controlled mainly by ________________.
  • a)
    CO2 level in blood
  • b)
    pH in blood
  • c)
    O2 level in blood
  • d)
    O2 level and pH in blood
Correct answer is option 'A'. Can you explain this answer?

Raghav Bansal answered
Rate of breathing is mainly controlled by CO2 level in the blood.
Excess CO2 decrease the pH of the blood and it mainly stimulate the respiratory centre of the brain (i.e., Medulla oblongata) and increase the inspiratory and expiratory signals to the respiratory muscles.

Aquatic arthropods and mollusks use which organ for respiration?
  • a)
    Lungs
  • b)
    Gills
  • c)
    Eyes
  • d)
    Nose
Correct answer is option 'B'. Can you explain this answer?

EduRev NEET answered
  • Since aquatic arthropods and mollusks are mainly in water, they use gills for respiration.
  • These gills are present as outgrowths to their skin, which is covered by the exoskeleton.
  • The exchange of gases takes place through these gills.

 After taking a long deep breath we do not respire for some seconds due to
  • a)
    More CO2 in blood
  • b)
    More O2 in blood
  • c)
    Less CO2 in blood
  • d)
    Less O2 in blood
Correct answer is option 'C'. Can you explain this answer?

Riya Banerjee answered
Blood cannot become more than 100% saturated with oxygen. In deep breathing more carbon dioxide is washed out of the blood. This makes oxygen cling more strongly to haemoglobin in red blood cells and therefore oxygen delivery to the tissues is made worse and causes oxygen toxicity. But comparatively, more carbon dioxide levels can improve oxygen delivery. Hence lungs keep carbon dioxide levels high in inhaled air and therefore in the blood.

Fill up the blanks in the following paragraph by selecting the correct option.
Human beings have a significant ability to maintain and moderate the respiratory rhythm to suit the demands of the body tissues. This is done by the neural system. A specialised centre present in the medulla region of the brain called ___(i) is primarily responsible for this regulation. Another centre present in the pons region of the brain called ___(ii)can moderate the functions of the respiratory rhytm centre. Neutral signal from this centre cen reduce the duration of )___(iii) and thereby alter the respiratory rate. A ___(iv) is situated adjacent to the rhythm centre which is highly sensitive to CO2 and hydrogen ions.
  • a)
    (i)Chemosensitive area (ii)Respiratory rhythm centre (iii)Expiration (iv)Pneumotaxic centre
  • b)
    (i)Respiratory rhythm centre (ii)Pneumotaxic centre (iii)Inspiration (iv)Chemosensitive area
  • c)
    (i)Respiratory (ii)Chemosensitive area (iii)Expiration (iv)Pneumotaxic centre
  • d)
    (i)Pneumotaxic centre (ii)Chemosensitive area (iii)Inspiration (iv)Respiratory rhythm centre
Correct answer is option 'B'. Can you explain this answer?

Ananya Das answered
Human beings have a significant ability to maintain and moderate the respiratory rhythm, to suit the demands of the body tissues. This is done by the neural system. A specialised centre present in the medulla region of the brain called (i) Respiratory rhythm centre is primarily responsible for this regulation. Another centre present in the pons region of the brain called the (ii) Pneumotaxic centre can moderate the functions of the respiratory rhythm centre. A neural signal from this centre can reduce the duration of (iii) inspiration and thereby alter the respiratory rate. A chemosensitive (iv) area is situated adjacent to the rhythm centre which is highly sensitive to CO2 and hydrogen ions.
Correct answer is B.

The factor which does not affect the rate of alveolar diffusion is
  • a)
    solubility of gases
  • b)
    thickness of the membranes
  • c)
    pressure gradient
  • d)
    reactivity of the gases
Correct answer is option 'D'. Can you explain this answer?

Gaurav Kumar answered
O2 and CO2 are exchanged in the alveoli by simple diffusion. The factors that affect the diffusion are pressure gradient of the gases, solubility of the gases and the thickness of the membranes involved in diffusion.

Which of the following statements is correct?
  • a)
    The contraction of internal intercostal muscles lifts up the ribs and sternum.
  • b)
    The RBCs transport oxygen only.
  • c)
    The thoracic cavity is anatomically an air tight chamber.
  • d)
    Healthy man can inspire approximately 500 mL of air per minute.
Correct answer is option 'C'. Can you explain this answer?

Suresh Iyer answered
The thoracic cavity is anatomically an air tight chamber as ft consists of lungs that further consist of air sacs in which the air remains trapped. The contraction of the external intercostal muscles lifts up the ribs and sternum. RBCs transport both O2 and CO2. Healthy man can inspire or expire 6000 to 8000 mL of air per minute.

Vital capacity of lungs is
  • a)
    IRV + ERV
  • b)
    IRV + ERV + TV - RV
  • c)
    IRV + ERV + TV + RV
  • d)
    IRV + ERV + TV
Correct answer is option 'D'. Can you explain this answer?

Lavanya Menon answered
Vital capacity is the maximum volume of air a person can breathe in after a forced expiration or the maximum volume of air a person can breathe out after a forced inspiration.This equals the inspiratory reserve volume (IRV) + expiratory reserve volume (ERV) + tidal volume (TV). Its value is 3400 mL - 4800 mL.

Select the sequence of steps in Respiration.
(A) Diffusion of gases (O2 and CO2) across alveolar membrane.
(B) Diffusion of O2 and CO2 between blood and tissues.
(C) Transport of gases by the blood
(D) Pulmonary ventilation by which atmospheric air is drawn in and CO2 rich alveolar air is released out.
(E) Utilisation of O2 by the cells for catabolic reactions are resultant release of CO2
Choose the correct answer from the options given below :
  • a)
    (D), (A), (C), (B), (E)
  • b)
    (C), (B), (A), (E), (D)
  • c)
    (B), (C), (E), (D), (A)
  • d)
    (A), (C), (B), (E), (D)
Correct answer is option 'A'. Can you explain this answer?

EduRev NEET answered
he correct answer is Option A : (D), (A), (C), (B), (E).
Here's the reasoning behind this order :
(D) Pulmonary ventilation by which atmospheric air is drawn in and CO2 rich alveolar air is released out.
Respiration begins with pulmonary ventilation (breathing), which allows the atmospheric air to enter the lungs and CO2-rich air to be exhaled.
(A) Diffusion of gases (O2 and CO2) across the alveolar membrane.
Inside the lungs, oxygen diffuses from the alveoli into the blood, and carbon dioxide diffuses from the blood into the alveoli across the alveolar membrane.
(C) Transport of gases by the blood.
Once in the bloodstream, oxygen and carbon dioxide are transported to and from the body's tissues.
(B) Diffusion of O2 and CO2 between blood and tissues.
Oxygen diffuses from the blood into the body's tissues, and carbon dioxide diffuses from the tissues into the blood.
(E) Utilisation of O2 by the cells for catabolic reactions and resultant release of CO2.
Finally, oxygen is used by cells for metabolic processes, creating carbon dioxide as a byproduct.
Therefore, the sequence is (D), (A), (C), (B), (E).

Fetal haemoglobin has X affinity for oxygen than that of mother's haemoglobin during gestation. X is
  • a)
    same
  • b)
    higher
  • c)
    lower
  • d)
    lower affinity earlier but higher later
Correct answer is option 'B'. Can you explain this answer?

Understanding Fetal Hemoglobin
Fetal hemoglobin (HbF) is essential for effective oxygen transport from the mother to the fetus during gestation. Its structure and affinity for oxygen differ from adult hemoglobin (HbA).
Higher Affinity for Oxygen
- HbF has a higher affinity for oxygen compared to maternal hemoglobin (HbA).
- This increased affinity allows the fetus to extract oxygen from maternal blood effectively, even in lower oxygen environments.
Why Higher Affinity?
- The structural differences between HbF and HbA contribute to this higher affinity.
- HbF contains two alpha and two gamma chains, while HbA consists of two alpha and two beta chains.
- The gamma chains in HbF reduce the binding of 2,3-bisphosphoglycerate (2,3-BPG), a molecule that decreases hemoglobin's affinity for oxygen. This reduction leads to a greater affinity for oxygen.
Physiological Significance
- The higher oxygen affinity of HbF is crucial for fetal development, ensuring adequate oxygen supply for growth and metabolism.
- As the fetus develops and approaches birth, HbF gradually transitions to HbA, which has a lower affinity for oxygen. This transition prepares the newborn for breathing air.
Conclusion
In summary, fetal hemoglobin has a higher affinity for oxygen than maternal hemoglobin throughout gestation. This property is vital for ensuring the fetus receives sufficient oxygen for development, highlighting the remarkable adaptation of human physiology during pregnancy.

In the tissues, high concentrations of carbon dioxide
  • a)
    increases the affinity of haemoglobin to both oxygen and hydrogen
  • b)
    increases the affinity of haemoglobin to oxygen but decreases its affinity to hydrogen
  • c)
    decreases the affinity of haemoglobin to oxygen but increases its affinity to hydrogen
  • d)
    decreases the affinity of haemoglobin to both oxygen and hydrogen
Correct answer is option 'C'. Can you explain this answer?

Hansa Sharma answered
Increase in the CO2 content of the blood decreases the pH of the blood. This decreases the affinity of O2  with Hb. This is called Bohr effect and is closely related to the fact that deoxygenated Hb binds hydrogen ions more actively than does the Hb. This facilitates gaseous exchange because more O2 is released in the tissues where the amount of CO2 is more due to metabolic activity. At the same time, more O2 is taken up by the lungs or gills when the amount of CO2 is low.

The enzyme that increases the reaction rate between CO2 and H2O in red blood cell is
  • a)
    carbonic anhydrase
  • b)
    adenylate cyclase
  • c)
    carbonic synthetase
  • d)
    alkaline phosphatase
Correct answer is option 'A'. Can you explain this answer?

Meera Singh answered
About 70% of CO2 is transported in plasma in the form bof bicarbonates, CO2 diffuses into RBCs, combines with water and form carbonic acid. Carbonic acid being unstable quickly dissociates into bicarbonate ions and hydrogen ions. This reaction is thousand times faster in RBCs as compared to plasma, as RBCs contain carbonic anhydrase enzyme that reversibe catalyses the conversion of CO2 and water to carbonic acid.

The urge to inhale in humans results from
  • a)
    rising PCO2
  • b)
    rising PO2
  • c)
    falling PCO2
  • d)
    falling PO2
Correct answer is option 'A'. Can you explain this answer?

Preeti Iyer answered
Excess CO2 mainly stimulates the respiratory centre of the brain and increase the inspiratory and expiratory signal to the respiratory muscles. O2 does not have a significant direct effect on the respiratory centre of the brain in controlling respiration.

Which of the following would have the same O2 content?
  • a)
    Blood entering the lungs and blood leaving the lungs
  • b)
    Blood entering the right side of the heart and blood leaving the right side of the heart
  • c)
    Blood entering the right side of the heart and blood leaving the left side of the heart
  • d)
    Blood entering the tissue capillaries and blood leaving the tissue capillaries
Correct answer is option 'B'. Can you explain this answer?

Riya Banerjee answered
Blood entering the right side of the heart le., right atrium is a deoxygenated blood having partial pressure of 40 mm Hg. Blood,leaving the right side of the heart i.e., right ventricle will also have almost same partial pressure as the blood is moving from right atrium to right ventricle and also no exchange of gases occurs in this path.

Which of the following structures close the glottis during swallowing to prevent the entry of food wind pipe
  • a)
    Tongue
  • b)
    Epiglottis
  • c)
    Diaphragm
  • d)
    Larynx
Correct answer is option 'B'. Can you explain this answer?

Ananya Das answered
Epiglottis is a leaf shaped cartilage that closes the glottis (opening leading into tarachea) to cheak the entry of food into it during swallowing. If during eating epiglottis remains open, then food particles may center the trachea (wind pipe) lending to reflex action of couhing. This removes the food particles from traches so that breathing does not get obstructed.

Which of the following sequence is correct to invite inspiration?
(i) the contraction of external intercostal muscles raises the ribs and sternum
(ii) Volume of thorax increases in the dorso-ventral axis
(iii) intrapulmonary pressure decreases
(iv) Diaphragm contraction
(v) Air rushes into lungs
(vi) Volume of thorax increases in the anterior-posterior axis
  • a)
    (i), (ii), (iv), (v), (iii), (vi)
  • b)
    (i), (ii), (iii), (iv), (vi), (v)
  • c)
    (i), (ii), (iv), (vi), (iii), (v)
  • d)
    (vi), (v), (i), (ii), (iii), (iv)
Correct answer is option 'C'. Can you explain this answer?

Krish Pillai answered


Explanation:

Sequence for inviting inspiration:

- (i) The contraction of external intercostal muscles raises the ribs and sternum
- (ii) Volume of thorax increases in the dorso-ventral axis
- (iv) Diaphragm contraction
- (vi) Volume of thorax increases in the anterior-posterior axis
- (iii) Intrapulmonary pressure decreases
- (v) Air rushes into lungs

Therefore, the correct sequence to invite inspiration is (i), (ii), (iv), (vi), (iii), (v). This sequence outlines the process of how inspiration occurs, starting with the contraction of external intercostal muscles and ending with the influx of air into the lungs. Each step in the sequence is crucial in creating a pressure difference that allows air to flow into the lungs during inspiration.

Pneumotaxic centre which can moderate the functions of the respiratory rhythm centre is present at
  • a)
    Pons region of brain
  • b)
    Thalamus
  • c)
    Spinal cord
  • d)
    Right cerebral hemisphere
Correct answer is option 'A'. Can you explain this answer?

Vivek Patel answered
The pneumotaxic centre, also known as the pontine respiratory group (PRG), is a network of neurons in the rostral dorsolateral pons. The PRG regulates the amount of air a person can take into the body in each breath. The absence of the PRG results in an increase in depth of respiration and a decrease in respiratory rate.

Which of the following changes occur in diaphragm and intercostal muscles when expiration of air takes place?
  • a)
    Internal intercostal muscles relex and diaphragm contracts
  • b)
    External intercostal muscles and diaphragm relax
  • c)
    Internal intercostal muscles contract and diaphragm relax
  • d)
    Internal intercostal muscles and diaphragma contract
Correct answer is option 'C'. Can you explain this answer?

Priya Menon answered
During expiration, the internal intercostal muscles contract, and the diaphragm relaxes. This is because the internal intercostal muscles contracting and the diaphragm relaxing decreases the volume of the thoracic cavity. This in turn decreases the volume of the lungs. 

When CO2 concentration in blood increases, breathing becomes
  • a)
    shallower and slow
  • b)
    there is no effect on breathing
  • c)
    slow and deep
  • d)
    faster and deeper
Correct answer is option 'D'. Can you explain this answer?

Partho Khanna answered
Factors affecting the binding of carbon dioxide with haemoglobin

Carbon dioxide (CO2) is a waste product of cellular respiration and is transported in the blood to the lungs for exhalation. The majority of CO2 is transported in the form of bicarbonate ions (HCO3-) in the plasma, but a small fraction directly binds to haemoglobin (Hb) in red blood cells. The binding of CO2 with Hb is influenced by various factors, including the partial pressure of carbon dioxide (pCO2).

Partial pressure of carbon dioxide (pCO2)
- The pCO2 is a measure of the concentration of carbon dioxide in the blood. It is the most important factor affecting the binding of CO2 with Hb.
- When the pCO2 is high, such as in tissues during cellular respiration, CO2 diffuses into red blood cells and binds to Hb, forming carbaminohemoglobin (HbCO2).
- The binding of CO2 to Hb occurs through a reversible reaction in which CO2 combines with the amino groups of the globin chains of Hb.
- The presence of CO2 in the blood helps in the release of oxygen (O2) from Hb, a phenomenon known as the Bohr effect.
- When the pCO2 is low, such as in the lungs, CO2 dissociates from Hb and is exhaled.

Other factors affecting the binding of CO2 with Hb
- While the pCO2 is the primary factor affecting the binding of CO2 with Hb, other factors can also have an impact:
- Partial pressure of oxygen (pO2): The binding of O2 and CO2 to Hb are inversely related. When pO2 is high, such as in the lungs, O2 binds to Hb, promoting the release of CO2. Conversely, when pO2 is low, such as in tissues, CO2 binds to Hb.
- Hydrogen ion concentration (pH): An increase in hydrogen ions (acidic conditions) decreases the affinity of Hb for O2, promoting the binding of CO2. This phenomenon is known as the Bohr effect.
- Temperature: An increase in temperature decreases the affinity of Hb for O2, favoring the binding of CO2. This effect is particularly important during exercise when body temperature rises.
- 2,3-bisphosphoglycerate (2,3-BPG): This molecule, present in red blood cells, binds to Hb and decreases its affinity for O2. As a result, more O2 is released from Hb, allowing for the binding of CO2.

In summary, the primary factor affecting the binding of CO2 with Hb is the partial pressure of carbon dioxide (pCO2). When pCO2 is high, CO2 binds to Hb, promoting the release of O2. Other factors such as pO2, pH, temperature, and 2,3-BPG also influence the binding of CO2 with Hb.

Identify the region of human brain which has pneumotaxic centre that alters respiratory rate by reducing the duration of inspiration.
  • a)
    Cerebrum
  • b)
    Medulla
  • c)
    Pons
  • d)
    Thalamus
Correct answer is option 'C'. Can you explain this answer?

Arya Bose answered
Pneumotaxic Centre in the Brain
The pneumotaxic centre is a crucial component of the brain's respiratory control system, located specifically in the pons.
Function of the Pneumotaxic Centre
- The pneumotaxic centre regulates the rhythm of breathing by influencing the duration of inspiration.
- By shortening the time taken for inhalation, it helps maintain a balanced respiratory rate.
Location and Structure
- The pons is situated above the medulla and below the midbrain.
- It plays a vital role in relaying signals between different parts of the brain and is integral to the control of autonomic functions.
Interaction with Other Centres
- The pneumotaxic centre works in conjunction with the apneustic centre, which promotes prolonged inhalation.
- This balance between the two centres ensures efficient breathing patterns, adapting to the body's needs during various activities.
Importance in Respiratory Health
- Proper functioning of the pneumotaxic centre is essential for maintaining homeostasis in respiratory activities.
- Dysregulation can lead to breathing disorders, affecting overall health.
In conclusion, the correct answer is option 'C', the pons, as it houses the pneumotaxic centre that modulates the duration of inspiration, thereby affecting the respiratory rate. Understanding this mechanism is crucial for fields related to medicine and physiology, particularly in contexts like NEET preparations.

When temperature decreases, oxy-Hb curve becomes 
  • a)
    more steep
  • b)
    straight
  • c)
    parabola
  • d)
    none of these
Correct answer is option 'A'. Can you explain this answer?

Ashwin Ghosh answered
Explanation:
When temperature decreases, the oxyhemoglobin (HbO2) dissociation curve becomes more steep.

Understanding the Oxy-Hb curve:
The oxyhemoglobin dissociation curve represents the relationship between the partial pressure of oxygen (PO2) and the saturation of hemoglobin with oxygen (SO2). It shows how readily hemoglobin binds to or releases oxygen molecules in response to changes in the partial pressure of oxygen.

Effect of temperature on Oxy-Hb curve:
Temperature affects the affinity of hemoglobin for oxygen. When the temperature decreases, the oxyhemoglobin dissociation curve shifts to the right, indicating a decreased affinity of hemoglobin for oxygen. This means that at any given partial pressure of oxygen, hemoglobin will release oxygen more readily.

Explanation of the answer:
When the temperature decreases, the oxyhemoglobin dissociation curve becomes more steep. This means that for a given decrease in partial pressure of oxygen, the amount of oxygen released by hemoglobin is greater compared to when the temperature is higher. This is because the decrease in temperature causes hemoglobin to have a lower affinity for oxygen, allowing it to release oxygen more readily.

Reason behind the steepening of the curve:
The steepening of the oxyhemoglobin dissociation curve with a decrease in temperature can be explained by the effect of temperature on the conformational changes in hemoglobin. Hemoglobin exists in two forms: the relaxed (R) form with high oxygen affinity and the tense (T) form with low oxygen affinity. When oxygen binds to hemoglobin, it stabilizes the R form, making it easier for other oxygen molecules to bind. On the other hand, when oxygen is released, it stabilizes the T form, making it easier for other oxygen molecules to be released.

A decrease in temperature stabilizes the T form of hemoglobin, reducing its affinity for oxygen and promoting the release of oxygen. This results in a more pronounced decrease in oxygen saturation for a given decrease in partial pressure of oxygen, leading to a steeper oxyhemoglobin dissociation curve.

In conclusion, when the temperature decreases, the oxyhemoglobin dissociation curve becomes more steep due to the decreased affinity of hemoglobin for oxygen, causing it to release oxygen more readily at any given partial pressure of oxygen.

During winter a person died during sleep, the room was closed and a container with burnt charcoal was found in the room. What may be the possible reason of his death?
  • a)
    Non-availability of oxygen
  • b)
    Hb has more affinity to combine with carbon monoxide
  • c)
    Hb has more affinity to combine with carbon dioxide
  • d)
    Combined effect of both (a) and (b)
Correct answer is option 'B'. Can you explain this answer?

Hansa Sharma answered
Charcoal on burning produces carbon monoxide (CO). CO has about 200 times more affinity for Hb than O2. On combining with Hb, it forms a stable compound carboxyhaemoglobin. Because of this compound, Hb cannot carry sufficient O2 to the tissues ultimately leading to death.

During CO2 transport, HCO3- diffuses from erythrocytes to plasma and in turn upsets the onic balance momentarily. In order to keep the ionic balance, an equal number of Cl pass into the erythrocytes from plasma. The process is known as
  • a)
    Hamburger phenomenon
  • b)
    Bicarbonate shift
  • c)
    Carbonation
  • d)
    Bohr's effect
Correct answer is option 'A'. Can you explain this answer?

Suresh Iyer answered
About 70% of CO2 is converted to bicarbonate ions (HCO3-) and transported in plasma. CO2 diffuses into RBCs, combines with-water and forms carbonic acid {H2CO3 ). H2CO3 being unstable quickly dissociates Into H+ and HCO3- . HCO3- ions are quite  diffusible. Therefore, HCO3-  diffuses from RBCs into the plasma. To maintain the ionic balance CI ions move from the plasma into the RBCs. This exchange is called chloride shift or Hamburger's phenomenon.
So, the correct answer is 'Hamburger phenomenon'.

The partial pressure of oxygen is maximum in
  • a)
    alveolar air
  • b)
    aterial blood
  • c)
    venous blood
  • d)
    expired air
Correct answer is option 'D'. Can you explain this answer?

Gaurav Kumar answered
The particle pressure of O2 in the expired air is 116mm Hg. In alveolar air it is 104mm Hg, in arterial blood it is 95mm Hg and in venous blood it is 40mm Hg.

One haemoglobin carries how many molecules of O2?
  • a)
    4
  • b)
    2
  • c)
    6
  • d)
    8
Correct answer is option 'A'. Can you explain this answer?

Raghav Bansal answered
Hb contains a protein portion called globin and a pigment portion called heam. The heam portion consists of four atoms of iron, each capable of combining with a molecule of O2, Thus, one Hb carries 4 molecules of O2

घास के मैदानों में, पेड़ पारिस्थितिक उत्तराधिकार के एक भाग के रूप में घास की जगह नहीं लेते हैं
  • a)
    कीड़े और कवक
  • b)
    सीमित धूप और पोषक तत्वों की कमी
  • c)
    पानी की सीमा और आग
  • d)
    इनमे से कोई भी नहीं
Correct answer is option 'C'. Can you explain this answer?

Neha Joshi answered
व्याख्या: घास के मैदान उष्णकटिबंधीय जंगलों और रेगिस्तान के बीच पारिस्थितिकी का प्रतिनिधित्व करते हैं। घास के मैदानों में घास कम नमी और उच्च तापमान के कारण घास की जगह नहीं लेती है जिसके परिणामस्वरूप घास के मैदानों में अक्सर आग लग जाती है। कीट और कवक घास के मैदानों में भी जीवित नहीं रह सकते हैं।
इसलिए विकल्प 3 सही उत्तर है।
शैक्षिक उद्देश्य: घास के मैदानों और सुविधाओं के जीवों और वनस्पतियों का अध्ययन करना।

Chemosensitive area of respiratory centre in medulla is affected by
  • a)
    Less CO2 and H+ ions
  • b)
    Less O2 and H+ ions
  • c)
    Excess CO2 and H+ ions
  • d)
    Excess O2 and H+ ions
Correct answer is option 'C'. Can you explain this answer?

Gaurav Kumar answered
Respiratory rhythm centre is a specialised centre present in the medulla of the brain which is primarily responsible for the regulation of respiration. A chemosensitive area situated adjacent to the rhythm centre is highly sensitive to changes in CO2 and hydrogen ion concentrations in blood. Increase in CO2 and H+ ions stimulate this centre, which in turn stimulate the rhythm centre to make necessary adjustments in the respiratory process by which these substances can be eliminated.

Which of the following statements is true about RBCs in humans?
  • a)
    They carry about 20-25 per cent of CO2
  • b)
    They transport 99.5 per cent of O2
  • c)
    They transport about 80 per cent oxygen only and the rest 20 per cent of it is transported in dissolved state in blood-plasma
  • d)
    They do not carry CO2 at all
Correct answer is option 'A'. Can you explain this answer?

Preeti Iyer answered
Nearly 20-25% of CO2 is transported by RBCs whereas 70% of it is carried as bicarbonate in plasma. About 7% of COis carried in a dissolved state through plasma. About 97% of Ois carried by RBCs in the blood. About 3% of O2 is transported in a dissolved state through the plasma.

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