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Which antibiotic inhibits interaction between RNA and mRNA during bacterial protein synthesis? [2006]
  • a)
    Neomycin
  • b)
    Streptomycin
  • c)
    Tetracycline
  • d)
    Erythromycin
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Which antibiotic inhibits interaction between RNA and mRNA during bact...
Neomycin is the antibiotic which inhibit the translation of bacterial cell so that it can not affect the host cell.
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Which antibiotic inhibits interaction between RNA and mRNA during bact...
Answer:

Introduction:
Antibiotics are medications used to treat bacterial infections by inhibiting the growth or killing bacteria. Different antibiotics target different aspects of bacterial physiology or metabolism to exert their antimicrobial effects. In the case of bacterial protein synthesis, several antibiotics interfere with the interaction between RNA and mRNA, thereby preventing the synthesis of essential proteins required for bacterial survival.

Explanation:
The antibiotic neomycin is known to inhibit the interaction between RNA and mRNA during bacterial protein synthesis.

Neomycin:
- Neomycin belongs to the class of aminoglycoside antibiotics.
- It is derived from the bacterium Streptomyces fradiae.
- Neomycin works by binding to the bacterial ribosome, specifically the 30S subunit.
- This binding interferes with the initiation complex formation during translation, preventing the correct alignment of the mRNA with the ribosome.
- As a result, protein synthesis is inhibited, leading to bacterial growth arrest and eventual death.

Other options:
- Streptomycin is another aminoglycoside antibiotic, but it inhibits protein synthesis by binding to the 30S subunit and causing misreading of the genetic code.
- Tetracycline inhibits protein synthesis by binding to the 30S subunit and preventing the binding of aminoacyl-tRNA to the A site of the ribosome.
- Erythromycin is a macrolide antibiotic that inhibits protein synthesis by binding to the 50S subunit of the bacterial ribosome and preventing translocation.

Conclusion:
In summary, neomycin is the antibiotic that inhibits the interaction between RNA and mRNA during bacterial protein synthesis. By interfering with the initiation complex formation, neomycin disrupts the normal process of translation, leading to bacterial growth inhibition and death.
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Which antibiotic inhibits interaction between RNA and mRNA during bacterial protein synthesis? [2006]a)Neomycinb)Streptomycinc)Tetracyclined)ErythromycinCorrect answer is option 'A'. Can you explain this answer?
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