Hybridoma cells are[1999]a)nervous cells of frogb)hybrid cells resulti...
Myeloma is a type of cancer associated with abnormal production of irregular antibodies. It occurs in antibody producing cells that have lost their normal control. Hybridomas are clones of hybrid cell resulting from fusion of normal antibody producing B-cells with myeloma cells.
View all questions of this test
Hybridoma cells are[1999]a)nervous cells of frogb)hybrid cells resulti...
Hybridoma cells are
Hybridoma cells are a type of hybrid cells resulting from the fusion of myeloma cells and B cells. They are widely used in biomedical research and the production of monoclonal antibodies.
Explanation:
Hybridoma cells are created through a laboratory technique called hybridoma technology. This technique involves fusing a specific type of cancerous B cell called a myeloma cell with an antibody-producing B cell. The resulting hybrid cells, known as hybridomas, possess the ability to continuously produce large quantities of a specific antibody called a monoclonal antibody.
1. Myeloma cells:
Myeloma cells are cancerous plasma cells that are derived from B cells. They are used in hybridoma technology due to their ability to grow indefinitely in culture and produce large amounts of a single type of antibody.
2. B cells:
B cells are a type of white blood cell that plays a crucial role in the immune response. They are responsible for producing antibodies, which are proteins that recognize and bind to specific foreign substances in the body, such as bacteria or viruses.
3. Fusion:
In the hybridoma technology, myeloma cells and B cells are fused together using a technique called cell fusion. This fusion results in the formation of hybridoma cells that possess the characteristics of both parent cells.
4. Continuous antibody production:
The hybridoma cells are capable of continuously producing large quantities of a specific antibody. This is because the myeloma cells provide the immortalization property, allowing the hybridomas to grow indefinitely in culture, while the B cells contribute the ability to produce antibodies.
5. Monoclonal antibodies:
Monoclonal antibodies are antibodies that are derived from a single clone of hybridoma cells. They are highly specific and can bind to a particular target molecule, such as a protein or a cell surface marker. Monoclonal antibodies have various applications in research, diagnostics, and therapeutics.
Therefore, the correct answer is option B: Hybridoma cells resulting from myeloma cells. Hybridoma cells are not nervous cells, do not exclusively possess oncogenes, and are not a product of spore formation in bacteria.
To make sure you are not studying endlessly, EduRev has designed NEET study material, with Structured Courses, Videos, & Test Series. Plus get personalized analysis, doubt solving and improvement plans to achieve a great score in NEET.