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Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?
- a)b-galactosidase
- b)Lactose permease
- c)Transacetylase
- d)Lactose permease and transacetylase
Correct answer is option 'A'. Can you explain this answer?
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Which enzyme/s will be produced in a cell in which there is a non-sens...
Non sense mutation is point mutation which result in premature stop codon so transcription stop there.
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Which enzyme/s will be produced in a cell in which there is a non-sens...
Understanding the Lac Operon
The lac operon is a crucial system in E. coli that enables the utilization of lactose. It consists of three structural genes: lacZ, lacY, and lacA. Each gene encodes a specific enzyme.
Key Components of the Lac Operon
- lacZ: Encodes β-galactosidase, which breaks down lactose into glucose and galactose.
- lacY: Encodes lactose permease, which facilitates the transport of lactose into the cell.
- lacA: Encodes transacetylase, involved in the detoxification of by-products.
Impact of a Non-sense Mutation in lacY
A non-sense mutation in the lacY gene introduces a premature stop codon, leading to a truncated protein. This results in:
- Loss of Lactose Permease Production: The lactose permease protein is not synthesized, hence lactose cannot be effectively transported into the cell.
Production of Other Enzymes
Despite the non-sense mutation in lacY, the lacZ and lacA genes remain intact:
- β-galactosidase (lacZ): This enzyme can still be produced since the mutation does not affect its gene. Therefore, β-galactosidase can still be synthesized.
- Transacetylase (lacA): Similarly, this enzyme is also unaffected by the lacY mutation and can still be produced.
Conclusion
In summary, a non-sense mutation in the lacY gene results in the absence of lactose permease. However, β-galactosidase and transacetylase can still be produced because their respective genes (lacZ and lacA) are unaffected. Hence, the correct answer is option 'A' – β-galactosidase will be produced in the cell.
The lac operon is a crucial system in E. coli that enables the utilization of lactose. It consists of three structural genes: lacZ, lacY, and lacA. Each gene encodes a specific enzyme.
Key Components of the Lac Operon
- lacZ: Encodes β-galactosidase, which breaks down lactose into glucose and galactose.
- lacY: Encodes lactose permease, which facilitates the transport of lactose into the cell.
- lacA: Encodes transacetylase, involved in the detoxification of by-products.
Impact of a Non-sense Mutation in lacY
A non-sense mutation in the lacY gene introduces a premature stop codon, leading to a truncated protein. This results in:
- Loss of Lactose Permease Production: The lactose permease protein is not synthesized, hence lactose cannot be effectively transported into the cell.
Production of Other Enzymes
Despite the non-sense mutation in lacY, the lacZ and lacA genes remain intact:
- β-galactosidase (lacZ): This enzyme can still be produced since the mutation does not affect its gene. Therefore, β-galactosidase can still be synthesized.
- Transacetylase (lacA): Similarly, this enzyme is also unaffected by the lacY mutation and can still be produced.
Conclusion
In summary, a non-sense mutation in the lacY gene results in the absence of lactose permease. However, β-galactosidase and transacetylase can still be produced because their respective genes (lacZ and lacA) are unaffected. Hence, the correct answer is option 'A' – β-galactosidase will be produced in the cell.
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Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?a)b-galactosidaseb)Lactose permeasec)Transacetylased)Lactose permease and transacetylaseCorrect answer is option 'A'. Can you explain this answer?
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Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?a)b-galactosidaseb)Lactose permeasec)Transacetylased)Lactose permease and transacetylaseCorrect answer is option 'A'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?a)b-galactosidaseb)Lactose permeasec)Transacetylased)Lactose permease and transacetylaseCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?a)b-galactosidaseb)Lactose permeasec)Transacetylased)Lactose permease and transacetylaseCorrect answer is option 'A'. Can you explain this answer?.
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