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Based on the behavior of the Metalloenzymes, consider the following statements:           
  • a)
    In the enzymes, the zinc activates O2 to form peroxide species.           
  • b)
    In the enzymes, the zinc activates H2O and provides a zinc bond hydroxide           
  • c)
    In the oxidases, the iron activates O2 to break the bonding between the two oxygens           
  • d)
    Zinc ion acts as a nucleophile and attacks at the peptide carbonyl
Correct answer is option 'B,C'. Can you explain this answer?
Most Upvoted Answer
Based on the behavior of the Metalloenzymes, consider the following st...
Metalloenzymes and their behavior:

Metalloenzymes are enzymes that require a metal ion as a cofactor to carry out their biological functions. Metal ions such as zinc and iron play a crucial role in catalyzing the enzymatic reactions. The behavior of metalloenzymes depends on the type of metal ion present in the enzyme and the nature of the reaction being catalyzed.

Activation of O2 and H2O:

a) In the enzymes, the zinc activates O2 to form peroxide species:
Zinc ion can activate molecular oxygen (O2) to form peroxide species. This activation of O2 by the zinc ion is essential for the function of certain enzymes such as carbonic anhydrase and alcohol dehydrogenase.

b) In the enzymes, the zinc activates H2O and provides a zinc bond hydroxide:
Zinc ion can also activate water (H2O) and form a zinc bond hydroxide. This activation of water by the zinc ion is important for the function of enzymes such as alkaline phosphatase and carbonic anhydrase.

c) In the oxidases, the iron activates O2 to break the bonding between the two oxygens:
In oxidases, iron ion can activate O2 to break the bonding between the two oxygens. This activation of O2 by the iron ion is crucial for the function of enzymes such as cytochrome c oxidase and catalase.

Zinc ion as a nucleophile:

d) Zinc ion acts as a nucleophile and attacks at the peptide carbonyl:
Zinc ion can act as a nucleophile and attack the peptide carbonyl group in certain enzymes such as carboxypeptidase A. This attack by the zinc ion helps in the cleavage of the peptide bond.

Conclusion:

In summary, metalloenzymes play a crucial role in various biological processes. The behavior of metalloenzymes depends on the type of metal ion present in the enzyme and the nature of the reaction being catalyzed. Zinc and iron are two of the most common metal ions found in metalloenzymes, and they can activate O2 and H2O to form peroxide species and zinc bond hydroxide, respectively. Additionally, zinc ion can act as a nucleophile and attack the peptide carbonyl group in certain enzymes.
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Based on the behavior of the Metalloenzymes, consider the following statements:a)In the enzymes, the zinc activates O2 to form peroxide species.b)In the enzymes, the zinc activates H2O and provides a zinc bond hydroxidec)In the oxidases, the iron activates O2 to break the bonding between the two oxygensd)Zinc ion acts as a nucleophile and attacks at the peptide carbonylCorrect answer is option 'B,C'. Can you explain this answer?
Question Description
Based on the behavior of the Metalloenzymes, consider the following statements:a)In the enzymes, the zinc activates O2 to form peroxide species.b)In the enzymes, the zinc activates H2O and provides a zinc bond hydroxidec)In the oxidases, the iron activates O2 to break the bonding between the two oxygensd)Zinc ion acts as a nucleophile and attacks at the peptide carbonylCorrect answer is option 'B,C'. Can you explain this answer? for Chemistry 2024 is part of Chemistry preparation. The Question and answers have been prepared according to the Chemistry exam syllabus. Information about Based on the behavior of the Metalloenzymes, consider the following statements:a)In the enzymes, the zinc activates O2 to form peroxide species.b)In the enzymes, the zinc activates H2O and provides a zinc bond hydroxidec)In the oxidases, the iron activates O2 to break the bonding between the two oxygensd)Zinc ion acts as a nucleophile and attacks at the peptide carbonylCorrect answer is option 'B,C'. Can you explain this answer? covers all topics & solutions for Chemistry 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Based on the behavior of the Metalloenzymes, consider the following statements:a)In the enzymes, the zinc activates O2 to form peroxide species.b)In the enzymes, the zinc activates H2O and provides a zinc bond hydroxidec)In the oxidases, the iron activates O2 to break the bonding between the two oxygensd)Zinc ion acts as a nucleophile and attacks at the peptide carbonylCorrect answer is option 'B,C'. Can you explain this answer?.
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