Consider the following- (a) In liver and RBC plasmodium reproduce asexually (b) Sexual stage of plasmodium develop inside mosquitohow many correct-a)only ab)only bc)both correctd)both wrongCorrect answer is option 'D'. Can you explain this answer?

Question

Consider the following- (a) In liver and RBC plasmodium reproduce asexually    (b) Sexual stage of plasmodium develop inside mosquitohow many correct-a)only ab)only bc)both correctd)both wrongCorrect answer is option 'D'. Can you explain this answer?

Answer

The given statement has two parts, one related to the asexual reproduction of Plasmodium and the other related to its sexual stage. Let's analyze each part separately.

Asexual reproduction of Plasmodium:

- Plasmodium is a protozoan parasite that causes malaria.
- It has a complex life cycle, involving both sexual and asexual reproduction stages.
- In the human host, Plasmodium reproduces asexually in the liver and red blood cells.
- This stage is responsible for the symptoms of the disease, such as fever, chills, and anemia.
- The asexual reproduction stage does not involve a mosquito vector.

Sexual stage of Plasmodium:

- The sexual stage of Plasmodium occurs inside the mosquito vector.
- When a mosquito bites an infected human, it ingests the Plasmodium gametocytes (sexual stage cells).
- These gametocytes then differentiate into male and female gametes inside the mosquito's gut.
- The male and female gametes fuse to form a zygote, which develops into a motile stage called ookinete.
- The ookinete then penetrates the mosquito's midgut wall and transforms into an oocyst.
- The oocyst produces thousands of sporozoites, which migrate to the mosquito's salivary glands.
- When the mosquito bites another human, the sporozoites are injected into the bloodstream, starting a new infection cycle.

Conclusion:

Based on the above analysis, both parts of the given statement are partially correct. Plasmodium does reproduce asexually in the liver and red blood cells of the human host, but it also has a sexual stage that occurs inside the mosquito vector. Therefore, the correct answer is option D, both wrong.

Answer

Man is the intermediate host for malaria, wherein the asexual phase of the life cycle occurs. The sporozoites inoculated by the infested mosquito initiate this phase of the cycle from the liver, and the latter part continues within the red blood cells, which results in the various clinical manifestations of the disease. With the mosquito bite, tens to a few hundred invasive sporozoites are introduced into the skin. Following the intradermal deposition, some sporozoites are destroyed by the local macrophages, some enter the lymphatics, and some others find a blood vessel. The type of reproduction found is asexual. The sporozoites that enter a lymphatic vessel reach the draining lymph node wherein some of the sporozoites partially develop into exoerythrocytic stages and may also prime the T cells to mount a protective immune response

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