Trick to Remember Mendelian Disorders:

Mendelian disorders are genetic disorders that follow the principles of Mendelian inheritance. They are caused by mutations in a single gene and can be inherited in a predictable manner. Here are some tricks to remember the different types of Mendelian disorders:

1. Autosomal Dominant Disorders:
Autosomal dominant disorders are caused by mutations in genes located on autosomes. The following are some tricks to remember the different types of autosomal dominant disorders:

- "Hunting for a Crown": Huntington's disease is an autosomal dominant disorder that affects the nervous system and causes progressive degeneration of brain cells.
- "Achilles is a Marfan": Marfan syndrome is an autosomal dominant disorder that affects the connective tissue and can cause a variety of symptoms, including long limbs, aortic aneurysms, and lens dislocation.
- "Familial Hypercholesterolemia is a Killer": Familial hypercholesterolemia is an autosomal dominant disorder that causes high levels of LDL cholesterol and increases the risk of heart disease.

2. Autosomal Recessive Disorders:
Autosomal recessive disorders are caused by mutations in genes located on autosomes. The following are some tricks to remember the different types of autosomal recessive disorders:

- "PKU is a Cute Disease": Phenylketonuria (PKU) is an autosomal recessive disorder that affects the metabolism of phenylalanine and can cause intellectual disability. PKU babies have a musty odor.
- "Cystic Fibrosis is a Sticky Disease": Cystic fibrosis is an autosomal recessive disorder that affects the lungs, pancreas, and other organs. It causes thick, sticky mucus to build up in the lungs and digestive system.
- "Sickle Cell Disease is a Painful Disease": Sickle cell disease is an autosomal recessive disorder that affects the blood and causes the red blood cells to become sickle-shaped. This can cause pain, organ damage, and other complications.

3. X-Linked Disorders:
X-linked disorders are caused by mutations in genes located on the X chromosome. The following are some tricks to remember the different types of X-linked disorders:

- "Hemophilia is a Bleeder": Hemophilia is an X-linked recessive disorder that affects blood clotting and can cause excessive bleeding.
- "Duchenne is a Muscular Disease": Duchenne muscular dystrophy is an X-linked recessive disorder that causes progressive muscle weakness and wasting.
- "Color Blindness is a Guy Thing": Color blindness is an X-linked recessive disorder that affects color perception and is more common in males than females.

In conclusion, remembering Mendelian disorders can be challenging, but using tricks and associations can help. By associating each disorder with a memorable phrase or image, you can more easily recall the key features of each disorder.