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With reference to the PD1 blockades, consider the following statements:
1. It is related to the treatment of cancers.
2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.
Which of the statements given above is/are correct?
- a)1 only
- b)2 only
- c)Both 1 and 2
- d)Neither 1 nor 2
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
With reference to the PD1 blockades, consider the following statements...
In a medical trial, 12 patients in the United States were completely cured of rectal cancer without requiring any surgery or chemotherapy.
- The trial used a monoclonal antibody called dostarlimab every three weeks for six months for the treatment of a particular kind of stage two or three rectal cancer.
- The trial showed that immunotherapy alone – without any chemotherapy, radiotherapy, or surgery that have been staples of cancer treatment – could completely cure the patients with a particular kind of rectal cancer called ‘mismatch repair deficient’ cancer.
- ‘Mismatch repair deficient’ cancer is most common among colorectal, gastrointestinal, and endometrial cancers. Patients suffering from this condition lack the genes to correct typos in the DNA that occur naturally while cells make copies.
PD1 blockades
- The immunotherapy belongs to a category called PD1 blockades that are now recommended for the treatment of such cancers rather than chemotherapy or radiotherapy.
- PD1 is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity, and PD1 blockade therapy looks to release the T cells from this suppression.
Hence both statements are correct.
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With reference to the PD1 blockades, consider the following statements:1. It is related to the treatment of cancers.2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?
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With reference to the PD1 blockades, consider the following statements:1. It is related to the treatment of cancers.2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? for UPSC 2025 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about With reference to the PD1 blockades, consider the following statements:1. It is related to the treatment of cancers.2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? covers all topics & solutions for UPSC 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for With reference to the PD1 blockades, consider the following statements:1. It is related to the treatment of cancers.2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?.
With reference to the PD1 blockades, consider the following statements:1. It is related to the treatment of cancers.2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? for UPSC 2025 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about With reference to the PD1 blockades, consider the following statements:1. It is related to the treatment of cancers.2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? covers all topics & solutions for UPSC 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for With reference to the PD1 blockades, consider the following statements:1. It is related to the treatment of cancers.2. It is a type of protein that regulates certain functions of the immune system, including by suppressing T cell activity.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?.
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