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Which of the following cations is required for the conversion of prothrombin into active thrombin by thromboplastin?
  • a)
    Cu2+
  • b)
    Fe3+
  • c)
    Fe2+
  • d)
    Ca2+
Correct answer is option 'D'. Can you explain this answer?
Most Upvoted Answer
Which of the following cations is required for the conversion of prot...
Conversion of Prothrombin into Active Thrombin by Thromboplastin

Thromboplastin is an enzyme that is released from damaged tissues and initiates the clotting process by converting prothrombin into active thrombin. This conversion requires the presence of certain cations, including:

- Calcium ions (Ca2+)
- Magnesium ions (Mg2+)

Out of these two cations, calcium ions are the most important for the conversion of prothrombin into active thrombin. This is because calcium ions:

- Bind to thromboplastin and activate it, allowing it to convert prothrombin into thrombin
- Bind to certain clotting factors, including factor X, which is required for the formation of the prothrombinase complex that converts prothrombin into thrombin

Therefore, the correct answer to the question is option D, Ca2+.
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Community Answer
Which of the following cations is required for the conversion of prot...
Thrombokinase hydrolyses prothrombin to thrombin in presence of Ca2+ Thrombin converts soluble fibrinogen to insoluble fibrin.
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Which of the following cations is required for the conversion of prothrombin into active thrombin by thromboplastin?a)Cu2+b)Fe3+c)Fe2+d)Ca2+Correct answer is option 'D'. Can you explain this answer?
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