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With reference to Immune Imprinting, consider the following statements:
- It is a condition where the body tends to repeat its immune response based on the first variant it encountered.
- It acts as a database for the immune system to better respond the repeated infections.
Which of the statements given above is/are correct?
- a)1 Only
- b)2 Only
- c)Both 1 and 2
- d)Neither 1 nor 2
Correct answer is option 'C'. Can you explain this answer?
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Most Upvoted Answer
With reference to Immune Imprinting, consider the following statements...
Recent studies came out with the fact that Immune imprinting in the bodies, might be making new boosters dose of COVID-19 far less effective than expected.
- The phenomenon of Immune imprinting was first observed in 1947 when scientists noted that in flu patients and termed it an ‘original antigenic sin’.
- Immune imprinting is a tendency of the body to repeat its immune response based on the first variant it encountered — through infection or vaccination — when it comes across a newer or slightly different variant of the same pathogen.
- Imprinting acts as a database for the immune system, helping it put up a better response to repeat infections.
- After the body is exposed to a virus for the first time, it produces memory B cells that circulate in the bloodstream and quickly produce antibodies whenever the same strain of the virus infects again.
- The problem occurs when a similar, not identical, variant of the virus is encountered by the body.
- In such cases, the immune system, rather than generating new B cells, activates memory B cells, which produce cross-reactive antibodies that bind to features found in both the old and new strains.
Hence both statements are correct.
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With reference to Immune Imprinting, consider the following statements...
Explanation:
- Statement 1: It is a condition where the body tends to repeat its immune response based on the first variant it encountered.
- Statement 2: It acts as a database for the immune system to better respond to repeated infections.
Analysis:
Both statements are correct when discussing immune imprinting.
- Immune Imprinting: This phenomenon occurs when the immune system "remembers" the first variant of a pathogen it encountered and tends to repeat the same immune response upon subsequent encounters with similar variants. This is also known as immunological memory.
- Database for the Immune System: Immune imprinting essentially acts as a database for the immune system, allowing it to respond more effectively and efficiently to repeated infections by pathogens it has encountered before. The immune system can mount a quicker and stronger response due to this memory.
Therefore, both statements accurately describe the concept of immune imprinting and its role in shaping the immune response to infections.
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With reference to Immune Imprinting, consider the following statements: It is a condition where the body tends to repeat its immune responsebased on the first variant it encountered. It acts as a database for the immune system to better respond the repeated infections.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?
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