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With reference to the Spinal Muscular Atrophy type-1, consider the following statements:
- It is a neurological condition caused by a defect in the SMN1 gene.
- Zolgensma is a medication that has been approved to treat this condition in children under the age of two.
Which of the statements given above is/are correct?
- a)1 Only
- b)2 Only
- c)Both 1 and 2
- d)Neither 1 nor 2
Correct answer is option 'C'. Can you explain this answer?
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With reference to theSpinal Muscular Atrophy type-1, consider the foll...
The paediatrics department at AIIMS Delhi recently wrote a recommendation letter for the father of an 11-month-old patient who is seeking financial assistance for the infant's treatment worth Rs 17.5 crore (USD 2.1 million) due to SMA (Spinal Muscular Atrophy) type-1.
- Spinal Muscular Atrophy is a neurological condition caused by a defect in the SMN1 gene.
- Normally, every person is born with a gene called SMN1 which produces a protein called SMN protein, in many cells in our body.
- This protein is essential for the normal functioning of nerve cells in the spinal cord called the ‘anterior horn cells.
- The anterior horn cells control the skeletal muscles essential for all our movements However, the absence of the SMN1 gene causes a reduction in the amount of SMN protein produced in anterior horn cells.
- Impacts of reduced SMN protein: The reduced quantity of SMN protein causes gradual death of anterior horn cells, and thus progressive weakness of muscles of limbs, trunk and breathing and swallowing muscles.
- Zolgensma: It is an artificially prepared SMN1 gene, coupled with an innocuous viral vector (AAV9) and administered as a single-dose intravenous infusion. This medicine is approved for use in children under two years of age only.
Hence both statements are correct.
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With reference to theSpinal Muscular Atrophy type-1, consider the following statements: It is a neurological condition caused by a defect in theSMN1gene. Zolgensma is a medication that has been approved to treat this condition in children under the age of two.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?
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With reference to theSpinal Muscular Atrophy type-1, consider the following statements: It is a neurological condition caused by a defect in theSMN1gene. Zolgensma is a medication that has been approved to treat this condition in children under the age of two.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? for UPSC 2024 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about With reference to theSpinal Muscular Atrophy type-1, consider the following statements: It is a neurological condition caused by a defect in theSMN1gene. Zolgensma is a medication that has been approved to treat this condition in children under the age of two.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? covers all topics & solutions for UPSC 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for With reference to theSpinal Muscular Atrophy type-1, consider the following statements: It is a neurological condition caused by a defect in theSMN1gene. Zolgensma is a medication that has been approved to treat this condition in children under the age of two.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?.
With reference to theSpinal Muscular Atrophy type-1, consider the following statements: It is a neurological condition caused by a defect in theSMN1gene. Zolgensma is a medication that has been approved to treat this condition in children under the age of two.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? for UPSC 2024 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about With reference to theSpinal Muscular Atrophy type-1, consider the following statements: It is a neurological condition caused by a defect in theSMN1gene. Zolgensma is a medication that has been approved to treat this condition in children under the age of two.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer? covers all topics & solutions for UPSC 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for With reference to theSpinal Muscular Atrophy type-1, consider the following statements: It is a neurological condition caused by a defect in theSMN1gene. Zolgensma is a medication that has been approved to treat this condition in children under the age of two.Which of the statements given above is/are correct?a)1 Onlyb)2 Onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?.
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