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Consider the following statements regarding somatic mutation:
  1. It is an alteration in the DNA sequence that occurs in the cells after conception.
  2. All somatic mutations are known to pass from parents to their children.
Which of the statements given above is/are correct?
  • a)
    1 only
  • b)
    2 only
  • c)
    Both 1 and 2
  • d)
    Neither 1 nor 2
Correct answer is option 'A'. Can you explain this answer?
Most Upvoted Answer
Consider the following statements regarding somatic mutation: It is an...
Statement 1: It is an alteration in the DNA sequence that occurs in the cells after conception.


Explanation:

Somatic mutations are alterations in the DNA sequence that occur in the cells of an organism after conception. These mutations can be caused by various factors such as exposure to radiation, chemicals, or errors during DNA replication. Somatic mutations can affect a single cell or a group of cells, and they are not inherited or passed on to future generations. Instead, these mutations are confined to the individual in which they occur.

Statement 2: All somatic mutations are known to pass from parents to their children.


Explanation:

This statement is incorrect. Somatic mutations are not passed from parents to their children. Unlike germline mutations that occur in the reproductive cells (sperm and egg) and can be transmitted to offspring, somatic mutations are specific to the individual in which they occur. They are not present in the reproductive cells and therefore cannot be inherited by future generations.

Conclusion:

Based on the explanations provided above, it can be concluded that only statement 1 is correct. Somatic mutations are alterations in the DNA sequence that occur in the cells after conception, but they are not passed from parents to their children.
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Community Answer
Consider the following statements regarding somatic mutation: It is an...
Scientists have known of somatic variants for many years, but recently there has been an explosion in the amount of data.
  • It is also known as somatic mutations which refer to alterations in the DNA sequence that occur in the cells of an individual’s body after conception.
  • Somatic genetic variants are important for a number of normal physiological processes. For example, the immune cells in our body, which produce antibodies, undergo an enormous amount of somatic changes to create diverse proteins.
Where do somatic mutations happen?
  • The change to a person’s DNA during a somatic mutation happens after fertilization in any cell of their body that isn't a sperm or egg cell (germ cells).
  • Cells continuously copy and replace themselves in humans.
  • If a mutation occurs, all cells that form from that affected cell will have that mutation in its DNA.
  • These mutations don’t pass from parents to their children (not hereditary) and happen sporadically or randomly.
  • Common somatic mutation conditions include: Skin cancer, Lung Cancer, Sturge-Weber and syndrome etc.
Hence only statement 1 is correct.
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