Syllabus for UPSC Medical Science Optional Paper I:

1. Human Anatomy:
- Gross anatomy of the following systems: musculoskeletal, cardiovascular, respiratory, gastrointestinal, genitourinary, endocrine and reproductive systems.
- Histology and microscopic anatomy of the following systems: musculoskeletal, cardiovascular, respiratory, gastrointestinal, genitourinary, endocrine and reproductive systems.
- Developmental anatomy of the following systems: musculoskeletal, cardiovascular, respiratory, gastrointestinal, genitourinary, endocrine and reproductive systems.

2. Human Physiology:
- Basic physiology of the following systems: musculoskeletal, cardiovascular, respiratory, gastrointestinal, genitourinary, endocrine and reproductive systems.
- Neurophysiology.
- Sensory organs.

3. General and Systemic Pathology:
- Cellular adaptations and disturbances.
- Inflammation and repair.
- Hemodynamic disorders.
- Immunopathology.
- Neoplasia.
- Infectious diseases.
- Genetic disorders.
- Environmental and nutritional diseases.
- Diseases of infancy and childhood.
- Disorders of the blood.
- Disorders of the immune system.
- Disorders of the cardiovascular system.
- Disorders of the respiratory system.
- Disorders of the gastrointestinal system.
- Disorders of the liver, gall bladder, and pancreas.
- Disorders of the kidney and urinary tract.
- Disorders of the male and female reproductive systems.
- Disorders of the endocrine system.
- Disorders of the musculoskeletal system.
- Disorders of the nervous system.
- Disorders of the skin.
- Disorders of the eye and ear.

4. Clinical Pharmacology:
- Principles of pharmacology.
- Autonomic nervous system drugs.
- Central nervous system drugs.
- Cardiovascular drugs.
- Drugs affecting the gastrointestinal system.
- Drugs affecting the respiratory system.
- Drugs affecting the endocrine system.
- Drugs affecting the reproductive system.
- Chemotherapy of infectious diseases.
- Chemotherapy of neoplastic diseases.
- Immunopharmacology.
- Toxicology.

5. Microbiology:
- General microbiology.
- Bacteriology.
- Virology.
- Mycology.
- Parasitology.

6. Forensic Medicine:
- Introduction to forensic medicine.
- Medical jurisprudence.
- Forensic pathology.
- Forensic psychiatry.
- Forensic toxicology.
- Forensic science and DNA fingerprinting.
- Clinical forensic medicine.

7. Social and Preventive Medicine:
- Concept of health and disease.
- Epidemiology.
- Communicable diseases.
- Non-communicable diseases.
- National health programs.
- Demography and family planning.
- Environmental health.
- Occupational health.
- Nutrition and health.
- Health education and communication.