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Which one of the following best describes the term ‘Exclusome’, seen in the news recently?
  • a)
    A type of cellular membrane in plant cells
  • b)
    A circular DNA structure found in bacterial cells
  • c)
    A form of genetic material in prokaryotes
  • d)
    An organelle in mammalian plasma cells
Correct answer is option 'D'. Can you explain this answer?
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Which one of the following best describes the term ‘Exclusome&rs...
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Which one of the following best describes the term ‘Exclusome&rs...
Researchers have recently identified a previously unknown compartment in mammalian cells named ‘exclusome’.
About Exclusome:
  • It is a newly discovered organelle in mammalian cells.
  • It is made up of DNA rings known as plasmids.
  • It is located within the cell plasma.
  • This is peculiar because eukaryotic cells (cells with nuclei) usually keep most of their DNA in the cell nucleus, where it is organized into chromosomes.
  • Instead, in the exclusome, it is organized into plasmids -small, circular DNA strands that can replicate independently of chromosomes and are usually found in bacteria and other microscopic organisms.
  • What has the discovery revealed?
  • Some of the plasmids that end up in the exclusome originate from outside the cell, while others—known as telomeric rings—come from the capped ends of chromosomes, the telomeres.
  • Particularly in certain cancer cells, the ones from the telomeres are regularly pinched off and joined together to form rings.
  • The cell nucleus weeds out such DNA rings and deposits them, together with the plasmids coming from outside the cell, in the cell plasma.
  • This proves that cells are capable of differentiating between DNA that is their own and still needed and DNA that is foreign or presumably no longer required, which they then eject from the nucleus.
  • In this way, the exclusome may have a protective function, guarding the cell’s genetic integrity.
What is an Organelle?
  • Organelles are small, specialized structures in cells that operate like organs by carrying out specific tasks.
  • Among the more important cell organelles are the nuclei, which store genetic information; mitochondria, which produce chemical energy; and ribosomes, which assemble proteins.
Hence option d is the correct answer.
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Which one of the following best describes the term ‘Exclusome’, seen in the news recently?a)A type of cellular membrane in plant cellsb)A circular DNA structure found in bacterial cellsc)A form of genetic material in prokaryotesd)An organelle in mammalian plasma cellsCorrect answer is option 'D'. Can you explain this answer?
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Which one of the following best describes the term ‘Exclusome’, seen in the news recently?a)A type of cellular membrane in plant cellsb)A circular DNA structure found in bacterial cellsc)A form of genetic material in prokaryotesd)An organelle in mammalian plasma cellsCorrect answer is option 'D'. Can you explain this answer? for UPSC 2024 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about Which one of the following best describes the term ‘Exclusome’, seen in the news recently?a)A type of cellular membrane in plant cellsb)A circular DNA structure found in bacterial cellsc)A form of genetic material in prokaryotesd)An organelle in mammalian plasma cellsCorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for UPSC 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which one of the following best describes the term ‘Exclusome’, seen in the news recently?a)A type of cellular membrane in plant cellsb)A circular DNA structure found in bacterial cellsc)A form of genetic material in prokaryotesd)An organelle in mammalian plasma cellsCorrect answer is option 'D'. Can you explain this answer?.
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