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What is the primary function of the RAD51 recombinase (RAD51) gene?
  • a)
    Packaging of DNA into chromatin structures
  • b)
    Homologous recombination and DNA repair
  • c)
    Cellular respiration
  • d)
    Prevention of DNA mutations
Correct answer is option 'B'. Can you explain this answer?
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What is the primary function of the RAD51 recombinase (RAD51) gene?a)P...
Researchers recently identified the RAD51 protein as a key player in preventing DNA re-replication.
About RAD51:
  • RAD51 recombinase (RAD51) is a gene that encodes a protein that functions in homologous recombination and DNA repair. 
  • RAD51 has the function of finding and invading homologous DNA sequences to enable accurate and timely DNA repair. 
  • Breaks in DNA can be caused by natural and medical radiation or other environmental exposures and also occur when chromosomes exchange genetic material in preparation for cell division. 
  • The RAD51 protein binds to the DNA at the site of a break and encases it in a protein sheath, which is an essential first step in the repair process.
  • In the nucleus of many types of normal cells, the RAD51 protein interacts with many other proteins, including BRCA1 and BRCA2, to fix damaged DNA.
  • The BRCA2 protein regulates the activity of the RAD51 protein by transporting it to sites of DNA damage in the nucleus.
  • The interaction between the BRCA1 protein and the RAD51 protein is less clear, although research suggests that BRCA1 may also activate RAD51 in response to DNA damage.
  • By helping repair DNA, these three proteins play a role in maintaining the stability of a cell's genetic information.
Hence option b is the correct answer.
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What is the primary function of the RAD51 recombinase (RAD51) gene?a)Packaging of DNA into chromatin structuresb)Homologous recombination and DNA repairc)Cellular respirationd)Prevention of DNA mutationsCorrect answer is option 'B'. Can you explain this answer?
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