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Consider the following statements with reference to the Marburg Virus Disease (MVD):
1. It is a rare and severe hemorrhagic fever, with an average case fatality rate of around 50%.
2. It affects both people and non-human primates.
Which of the statements given above is/are correct?
  • a)
    1 only
  • b)
    2 only
  • c)
    Both 1 and 2
  • d)
    Neither 1 nor 2
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
Consider the following statements with reference to the Marburg Virus ...
Experts worry that the world's deadliest cave, Kitum, located in Mount Elgon National Park in Kenya, may be home to the next pandemic, the Marburg virus, with the WHO flagging Marburg as “epidemic-prone”.
About Marburg Virus Disease (MVD):
  • It is a rare but severe hemorrhagic fever which affects both people and non-human primates.
  • MVD is caused by the Marburg virus, a genetically unique zoonotic (or, animal-borne) RNA virus of the filovirus family. 
  • It is in the same family as the virus that causes the Ebola virus disease. 
  • It was initially detected in 1967 after simultaneous outbreaks in Marburg and Frankfurt in Germany; and in Belgrade, Serbia.
  • Transmission:
  • Human infection with MVD initially results from prolonged exposure to mines or caves inhabited by Rousettus bats.
  • Once an individual is infected with the virus, Marburg can spread through human-to-human transmission via direct contact (through broken skin or mucous membranes) with the bloodsecretionsorgans, or other bodily fluids of infected people, and with surfaces and materials (e.g., bedding, clothing) contaminated with these fluids. 
  • Symptoms:
  • After an incubation period of 2-21 dayssymptom onset is sudden and marked by fever, chills, headache, and myalgia.
  • Around the fifth day after the onset of symptoms, a maculopapular rash, most prominent on the trunk (chest, back, stomach), may occur.
  • Nausea, vomiting, chest pain, a sore throat, abdominal pain, and diarrhoea may appear.
  • Symptoms become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive hemorrhaging, and multi-organ dysfunction.
  • The average MVD case fatality rate is around 50%. Case fatality rates have varied from 24% to 88% in past outbreaks, depending on the virus strain and case management.
  • Treatment:
  • There is no specific treatment for MVD. 
  • Early supportive care with rehydration, and symptomatic treatment improves survival. 
Hence both statements are correct.
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Consider the following statements with reference to the Marburg Virus Disease (MVD):1. It is a rare and severe hemorrhagic fever, with an average case fatality rate of around 50%.2. It affects both people and non-human primates.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?
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