Write a short note on antibodies (5mark)?
Antibodies:
Antibodies, also known as immunoglobulins, are Y-shaped proteins produced by the immune system in response to the presence of antigens. They play a crucial role in the immune response by recognizing and neutralizing harmful substances such as bacteria, viruses, and toxins. Here are some key points about antibodies:
Structure:
- Antibodies are made up of four protein chains: two heavy chains and two light chains.
- They have a variable region that binds specifically to antigens and a constant region that interacts with other components of the immune system.
Functions:
- Antibodies can neutralize pathogens by binding to them and preventing them from infecting cells.
- They can also mark pathogens for destruction by immune cells such as macrophages and natural killer cells.
- Antibodies play a key role in the adaptive immune response, providing long-lasting immunity against specific pathogens.
Types:
- There are five main classes of antibodies: IgG, IgM, IgA, IgD, and IgE.
- Each class of antibody has a different function in the immune response, such as IgG being the most abundant and providing long-term immunity.
Production:
- Antibodies are produced by B cells in response to exposure to antigens.
- B cells can differentiate into plasma cells, which are specialized cells that secrete antibodies in large quantities.
Importance:
- Antibodies are essential for the body's defense against infections and diseases.
- They are also used in diagnostic tests, such as ELISA, to detect the presence of specific antigens in the blood.
In conclusion, antibodies are crucial components of the immune system that play a vital role in protecting the body against harmful pathogens. Their ability to recognize and neutralize antigens makes them indispensable for maintaining health and fighting off infections.
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