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Table of contents |
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Introduction |
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Nucleophilic Substitutions in Pyrrole, Furan and Thiophene |
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Furans |
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Condensed Five-Membered Heterocycles |
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Vilsmeier–Haack Formylation with N,N-Dimethylformamide. |
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at position 5.
Electron-donating substituents (D) at the position “β” to the heteroatom generally cause substitution to take place at the 2-position.
Thiophenes
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Pyrrole, Furan and Thiophene Nucleophilic Substitution Reactions
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Fusing benzene ring with 2,3-positions of furan, pyrrole and thiophene leading to benzo[b]furan, indole and benzo[b]thiophene, respectively.
1. What are nucleophilic substitutions in pyrrole, furan, and thiophene? | ![]() |
2. How do nucleophilic substitutions in furans occur? | ![]() |
3. What are condensed five-membered heterocycles? | ![]() |
4. What is Vilsmeier-Haack formylation with N,N-dimethylformamide? | ![]() |
5. How do pyrrole, furan, and thiophene undergo nucleophilic substitution reactions? | ![]() |