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All questions of Biomolecules for JEE Exam

Synthesis of protein is controlled by:
  • a)
    Nucleotide
  • b)
    RNA
  • c)
    DNA
  • d)
    Nucleoside
Correct answer is option 'B'. Can you explain this answer?

Lavanya Menon answered
RNA can directly control the synthesis of proteins, hence can easily express the characters. DNA, however, is dependent on RNA for synthesis of proteins. The protein synthesising machinery has evolved around RNA.

Proteins can be classified into two types on the basis of their molecular shape i.e., fibrous proteins and globular proteins. Examples of globular proteins are :
(Multiple Answer Correct)
  • a)
    Insulin & Albumin
  • b)
    Myosin
  • c)
    Keratin
  • d)
    None of these
Correct answer is option 'A'. Can you explain this answer?

Divey Sethi answered
The correct answer is A and C.
The structure of protein which results when the chain of polypeptides coil around to give a spherical shape are known as globular protein. These proteins are soluble in water, e.g., insulin and albumin are globular protein.
 

The compound which gives red colour with Fehling’s solution?
  • a)
    Cellulose
  • b)
    Benzaldehyde
  • c)
    Cane sugar
  • d)
    Glucose
Correct answer is option 'D'. Can you explain this answer?

Knowledge Hub answered
Fehling's solution to make difference between carbohydrate and ketone functional grp and also used for differentiate reducing and non reducing sugar and as u know glucose is a reducing sugar so it will give red colour with fehling's solution (all monosachharides are reducing sugar).

The essential amino acid is:
  • a)
    Serine
  • b)
    Arginine
  • c)
    Alanine
  • d)
    Glycine
Correct answer is option 'B'. Can you explain this answer?

Naina Bansal answered
In humans, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them.

The enzyme pepsin hydrolyses:
  • a)
    polysaccharides to monosaccharides
  • b)
    glucose to ethyl alcohol
  • c)
    proteins to amino acids
  • d)
    fats to fatty acids
Correct answer is option 'C'. Can you explain this answer?

Krishna Iyer answered
The correct answer is Option C
Pepsin hydrolyses proteins to amino acid(polypeptide chains) and initiates protein digestion in the digestion process in humans.

Alpha helix is found in
  • a)
    RNA
  • b)
    Lipid
  • c)
    Carbohydrates
  • d)
    secondary proteins
Correct answer is option 'D'. Can you explain this answer?

Ræjû Bhæï answered
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a right hand-helix conformation in which every backbone N−H group hydrogen bonds to the backbone C=O. group of the amino acid located three or four residues earlier along the protein sequence.

Which base is present in RNA but not in DNA ? 
[AIEEE-2004] 
  • a)
    Uracil
  • b)
    Cytosine
  • c)
    Guanine
  • d)
    Thymine
Correct answer is option 'A'. Can you explain this answer?

Shreya Singh answered
It's Uracil....Uracil is present in RNA. but not in DNA ....whereas Thymine is present in DNA and not in RNA ..

The active form of vitamin D is:
  • a)
    Calcidiol                                                                                         
  • b)
    Calcitriol
  • c)
    Cholecalciferol                                                                            
  • d)
    Any of the above
  • e)
    None of the above
Correct answer is option 'B'. Can you explain this answer?

Rajdeep Saini answered
The active form of vitamin D is calcitriol.

Calcitriol, also known as 1,25-dihydroxyvitamin D3, is the active form of vitamin D in the body. It is the biologically active metabolite that is synthesized from calcidiol, also known as 25-hydroxyvitamin D3, which is the storage form of vitamin D.

Explanation:

1. Vitamin D and its forms:
Vitamin D is a fat-soluble vitamin that plays a crucial role in maintaining bone health and calcium homeostasis. It exists in several forms, including vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol), which are obtained from dietary sources or synthesized in the skin upon exposure to sunlight.

2. Conversion of vitamin D to its active form:
When vitamin D2 or D3 is ingested or synthesized, it undergoes a series of metabolic conversions in the liver and kidneys to become the active form of vitamin D. The first step involves hydroxylation in the liver, where vitamin D is converted to calcidiol (25-hydroxyvitamin D3) through the action of the enzyme 25-hydroxylase.

3. Activation of calcidiol to calcitriol:
The second and final step in the activation of vitamin D occurs in the kidneys. Calcidiol undergoes further hydroxylation by the enzyme 1-alpha-hydroxylase, resulting in the formation of calcitriol (1,25-dihydroxyvitamin D3). This conversion is tightly regulated by various factors, including parathyroid hormone (PTH), calcium levels, and phosphate levels.

4. Biological functions of calcitriol:
Calcitriol acts as a hormone and binds to the vitamin D receptor (VDR) in target tissues, such as the intestines, bones, and kidneys. It regulates the absorption of calcium and phosphate in the intestines, promotes bone mineralization by increasing calcium and phosphate uptake, and helps maintain normal blood calcium levels. Calcitriol also has non-skeletal functions, including modulation of immune responses and cell growth.

Conclusion:
In conclusion, the active form of vitamin D is calcitriol, which is synthesized from calcidiol through the action of 1-alpha-hydroxylase in the kidneys. Calcitriol plays a crucial role in maintaining calcium homeostasis and bone health, as well as other physiological processes in the body.

Glucose and fructose are:
  • a)
    Position isomers
  • b)
    Functional isomers
  • c)
    Chain isomers
  • d)
    Optical isomers
Correct answer is option 'B'. Can you explain this answer?

Tanvi Bose answered
Glucose and fructose are functional isomers of each other Because they have same molecular formula that is C6H12O6 But different functional group in their chemical formula. Glucose has aldehyde group while fructose has ketone as functional group.

Name the RNA molecules which is used to carry genetic information copied from DNA?
  • a)
    tRNA
  • b)
    mRNA
  • c)
    rRNA
  • d)
    snRNA
Correct answer is option 'B'. Can you explain this answer?

Because mRNA is called messanger RNA, which carries the information from DNA to synthesis of protein and other essential products in cell.

Purine derivative among the following bases is:
  • a)
    Uracil
  • b)
    Cytosine
  • c)
    Guanine
  • d)
    Thymine
Correct answer is option 'C'. Can you explain this answer?

Shail Chawla answered
Purine is a type of nitrogenous base found in DNA and RNA molecules. The purine bases are adenine and guanine. Among the given options, the purine derivative is:

c) Guanine

Explanation:

- Purine and pyrimidine are two types of nitrogenous bases found in DNA and RNA molecules.
- Purine bases are larger and have a double-ring structure, while pyrimidine bases are smaller and have a single-ring structure.
- Adenine and guanine are purine bases, while cytosine, thymine, and uracil are pyrimidine bases.
- Therefore, among the given options, the purine derivative is guanine.

Nucleoside differs from nucleotide with the absence of:
  • a)
    Pentose sugar and Nitrogenous base
  • b)
    Nitrogenous base
  • c)
    Phosphoric acid
  • d)
    Pentose sugar
Correct answer is option 'C'. Can you explain this answer?

Arun Khanna answered
The structure of nucleotide and nucleoside units are distinguished primarily by the presence (or lack thereof) of this phosphate group. Deoxyribose in DNA differs from the ribose found in RNA in that it has only a hydrogen atom in the same position that ribose has a hydroxyl (-OH) group.

Which of the following terms are correct about enzyme?
  • a)
    Proteins
  • b)
    Dinucleotides
  • c)
    carbohydrates
  • d)
    None of these
Correct answer is option 'A'. Can you explain this answer?

Suresh Kumar answered
Enzymes are made up of proteins...but Ribozyme is an exception to this as its made up of 23 sr RNA which is a nucleic acid...
And enzymes acts as biocatalyst...
so; more accurately option d comes out to be the answer.

Which of the following carbohydrate is an example of an oligosaccharide?
  • a)
    Cellulose
  • b)
    Lactose
  • c)
    Mannose
  • d)
    Glucose
Correct answer is option 'B'. Can you explain this answer?

Anjali Iyer answered
Lactose intolerance is the inability to break down a type of natural sugar called lactose. Lactose is commonly found in dairy products, such as milk and yogurt. A person becomes lactose intolerant when his or her small intestine stops making enough of the enzyme lactase to digest and break down the lactose.

Hydrolysis of sucrose is called:
  • a)
    Hydration
  • b)
    Inversion
  • c)
    Esterification
  • d)
    Saponification
Correct answer is option 'B'. Can you explain this answer?

Hydrolysis of sucrose is inversion because the angle of specific rotation of the plane polarized light changes from positive to negative value due to the presence of optical isomers of mixture of glucose and fructose sugar...

Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a __________.
  • a)
    monosaccharide
  • b)
    disaccharide
  • c)
    non-reducing sugar
  • d)
    Both b and c
Correct answer is option 'D'. Can you explain this answer?

Divey Sethi answered
The correct answer is option B & D.
One of the common disaccharides is sucrose which on hydrolysis gives an equimolar mixture of D−(+)− glucose and D−(−) fructose. These two monosaccharides are held together by a glycosidic linkage between Cl of α- glucose and C2 of β- fructose. Since the reducing groups of glucose and fructose are involved in glycosidic bond formation, sucrose is a non-reducing sugar.

Which of the following base is not found in DNA?
  • a)
    Uracil
  • b)
    Guanine
  • c)
    Cytosine
  • d)
    Adenine
Correct answer is option 'A'. Can you explain this answer?

Ritu Pal answered
Uracil is not found in DNA , as it Uracil has more base pair affinity to adenine , guanine and cytosine. Instead thymine is present in DNA.

Glucose reacts with acetic anhydride to form:
  • a)
    Monoacetate
  • b)
    Diacetate
  • c)
    Pentaacetate
  • d)
     
    Hexaacetate
Correct answer is option 'C'. Can you explain this answer?

Pooja Mehta answered
It forms glucose pentaacetate. The acetic anhydride esterifies with all the alcohol groups on the glucose ring.

The pyrimidine bases present in DNA are –  
[AIEEE 2006]
  • a)
    cytosine and guanine
  • b)
    cytosine and thymine
  • c)
    cytosine and uracil
  • d)
    cytosine and adenine
Correct answer is option 'B'. Can you explain this answer?

Manoj Sengupta answered
Thus, in DNA, the purines adenine (A) and guanine (G) pair up with the pyrimidines thymine (T) and cytosine (C), respectively. In RNA, the complement of adenine (A) is uracil (U) instead of thymine (T), so the pairs that form are adenine:uracil and guanine:cytosine.

Sucrose is a non-reducing sugar because:​
  • a)
    The -CHO group of glucose is not involved in glycosidic bond formation.
  • b)
    Two monosaccharide units are held together by a glycosidic linkage between C1 of α-glucose and C2 of β-fructose.
  • c)
    On hydrolysis, sucrose gives dextrorotatory and laevorotatory and the mixture is laevorotatory.
  • d)
    Sucrose is dextrorotatory.
Correct answer is option 'B'. Can you explain this answer?

Gowri Menon answered
Glucose and C2 of fructose, which does not have a free aldehyde or ketone group to undergo oxidation and reduction reactions.
c)Sucrose does not react with Benedict's reagent, which is used to detect the presence of reducing sugars.
d)Sucrose cannot be hydrolyzed by acid or enzyme into its constituent monosaccharides.

The Molisch test is a chemical test that determines the presence of:
  • a)
    All carbohydrates
  • b)
    Sucrose
  • c)
    Fructose
  • d)
    Glucose
Correct answer is option 'A'. Can you explain this answer?

Anjali Iyer answered
The Molisch test uses concentrated sulphuric acid as the dehydrating acid. This acid dehydrates all carbohydrates, so the test is used to distinguish between carbohydrates and non-carbohydrates. 

In fibrous proteins, polypeptide chains are held together by ___________.
  • a)
    van der Waals forces
  • b)
    disulphide linkage & hydrogen bonds
  • c)
    electrostatic forces of attraction
  • d)
    None of these
Correct answer is option 'B'. Can you explain this answer?

Neha Sharma answered
The correct answer are options B & D,
In fibrous proteins, polypeptide chains are held together by hydrogen and disulphide bonds, in parallel manner. Due to which fibre-like structure is obtained. Such proteins are generally known as fibrous proteins. These proteins are generally insoluble in water e.g., keratin, myosin.
 

On hydrolysis maltose gives:
  • a)
    One molecule of glucose and one molecule of galactose
  • b)
    Two molecules of fructose
  • c)
    One molecule of glucose and one molecule of fructose
  • d)
    Two molecules of glucose
Correct answer is option 'D'. Can you explain this answer?

Alok Mehta answered
On hydrolysis, maltose gives glucose with the help of maltase enzyme which works as a catalysis of the hydrolysis of the glycoside bond. 
Maltase is a disaccharide which will reduce sugar giving two molecules of glucose on hydrolysis. 
It will give alpha-D-glucose and alpha-D-glucose. 

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