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All questions of The Mitotic Cell Cycle for A Level Exam

What is the proper sequence in mitosis?
  • a)
    Anaphase, metaphase, telophase and prophase
  • b)
    Telophase, anaphase, metaphase and prophase
  • c)
    Metaphase, telophase, prophase and anaphase
  • d)
    Prophase, metaphase, anaphase and telophase
Correct answer is option 'D'. Can you explain this answer?

Baby Shark answered
Correct option is D. In mitosis the sequence is prophase(chromatids compact to form chromosome) metaphase (chromosomes atrange at metacentruc plate)anaphase (cromosomes separate )and then telophase(move towards opposite poles and Endoplasmic reticulum , cell wall, etc is again formed.)
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How many mitotic divisions are needed for a single cell to make 128 cells?
  • a)
    7
  • b)
    14
  • c)
    28
  • d)
    32
Correct answer is option 'A'. Can you explain this answer?

Ananya Das answered
Mitosis is a process of nuclear division in eukaryotic cells that occurs when a parent cell divides to produce two identical daughter cells. 
Hence the process of the division will be:
► 1 cell gives 2 daughter cells (1st mitosis)
► 2 cells give 4 daughter cells (2nd mitosis)
► 4 cells give 8 daughter cells (3rd mitosis)
► 8 cells give 16 daughter cells (4th mitosis)
► 16 cells give 32 daughter cells (5th mitosis)
► 32 cells give 64 daughter cells (6th mitosis)
► 64 cells give 128 daughter cells (7th mitosis)
Hence 7 mitotic divisions cell needed for a single cell to make 128 cells.

Human ------------- do not divide in brain after birth.
  • a)
    Nerve cells
  • b)
    Cartillage cells
  • c)
    Muscule cells
  • d)
    All of above
Correct answer is option 'A'. Can you explain this answer?

Krish Patel answered
Human nerve cells do not divide after birth. The neural system is the control system of the body which consists of highly specialized cells called neurons. Nerve cell does not divide because they do not have centrioles, so they cannot undergo mitosis and divide to form new cells.

A cell plate is laid during
  • a)
    Cytokinesis
  • b)
    Karyokinesis
  • c)
    Interphase
  • d)
    None of the above
Correct answer is 'A'. Can you explain this answer?

Suresh Iyer answered
  • Cytokinesis is the part of the cell division process during which the cytoplasm of a single eukaryotic cell divides into two daughter cells.
  • Cytoplasmic division begins during or after the late stages of nuclear division in mitosis and meiosis.
  • During cytokinesis the spindle apparatus partitions and transports duplicated chromatids into the cytoplasm of the separating daughter cells. It thereby ensures that chromosome number and complement are maintained from one generation to the next and that, except in special cases, the daughter cells will be functional copies of the parent cell. After the completion of the telophase and cytokinesis, each daughter cell enters the interphase of the cell cycle.

In between two walls of adjacent cells are seen
  • a)
    Cell wall
  • b)
    Cytoplasm
  • c)
    Middle lamellae
  • d)
    Plasma membrane
Correct answer is option 'C'. Can you explain this answer?

Gaurav Kumar answered
The middle lamella serves as a cementing layer between the primary walls of adjacent cells.
The primary wall is the cellulose-containing layer laid down by cells that are dividing and growing. 

Which of the phases of mitosis is the longest?
  • a)
    Telophase
  • b)
    Prophase
  • c)
    Anaphase
  • d)
    Metaphase
Correct answer is option 'B'. Can you explain this answer?

Vijay Bansal answered
Prophase and telophase are stages involved in mitosis or meiosis. During G2 phase division of centrioles, mitochondria and chloroplasts occurs.

Crossing over results the exchange of genetic material, which occurs between
  • a)
    Non-sister chromosomes
  • b)
    Sister chromatids
  • c)
    Non-homologous chromosome
  • d)
    Homologous chromosomes
Correct answer is option 'D'. Can you explain this answer?

Rohan Singh answered
Most organisms that undergo sexual reproduction contain two types of cells in their body – haploid and diploid cells. Diploid cells are seen in most parts of the body and contain two copies of every chromosome. Therefore, they contain two genes to determine the sequence of nearly every RNA or protein. Haploid cells are usually male or female gametes formed as a result of meiosis and are seen in sexual organs. They contain only one complete set of chromosomes and are designed to fuse with another haploid gamete to produce a diploid zygote – with one paternal and one maternal set of chromosomes. Though they code for the same genes, their DNA sequences can vary slightly from one another. For instance, the paternal chromosome may contain the genetic information to result in antigen A being present on red blood cells, while the maternal chromosome may code for antigen B. These two antigens are similar in function, but differ from each other marginally in their amino acid sequence.

How many chromosomes are present in the each cell of the onion root tip?
  • a)
    2 chromosomes
  • b)
    3 chromosomes
  • c)
    16 chromosomes
  • d)
    4 chromosomes
Correct answer is option 'C'. Can you explain this answer?

Rohit Jain answered
The root tip cells of onion were used to test the potentially genotoxic effects of Alprazolam. The test was carried out according to Fiskesjö protocol (4, 11-12) with some modifications. Common onion (Allium cepa L.) has eight pairs of relatively large chromosomes (2n = 16) that allows for the easy detection of CAs.

In some lower plants and social insects, the haploid cells are divided by
  • a)
    Mitosis
  • b)
    Cytokinesis
  • c)
    Meiosis
  • d)
    Karyokinesis
Correct answer is option 'A'. Can you explain this answer?

Nandini Patel answered
Mitosis or the equational division is usually restricted to the diploid cells only. However, in some lower plants and in some social insects haploid cells also divide by mitosis. It is very essential to understand the significance of this division in the life of an organism. Are you aware of some examples where you have studied about haploid and diploid insects? Mitosis results in the production of diploid daughter cells with identical genetic complement usually. The growth of multicellular organisms is due to mitosis. Cell growth results in disturbing the ratio between the nucleus and the cytoplasm. It therefore becomes essential for the cell to divide to restore the nucleo-cytoplasmic ratio. A very significant contribution of mitosis is cell repair. The cells of the upper layer of the epidermis, cells of the lining of the gut, and blood cells are being constantly replaced. Mitotic divisions in the meristematic tissues – the apical and the lateral cambium, result in a continuous growth of plants throughout their life.

Plants show mitotic divisions in
a)Haploid cells
b)Haploid cells and diploid cells
c)Somatic cells
d)Diploid cells
Correct answer is option 'B'. Can you explain this answer?

Pooja Mehta answered
Mitosis is the type of cell division that ensures equal distribution of genetic material in daughter cells.

Mitosis can occur both in diploid and haploid cells. The main function of mitosis is to make copies of cells for growth and regeneration.
If a haploid cell undergoes mitosis, which is something certain types of plant and fungus do as part of their normal life cycles, the end result is two identical haploid cells (n→n),

Some plants and fungi have their bodies composed of haploid cell .
EXAMPLE: Gametophyte of Bryophyte plants. It is produced from mitotic cell division of spores, which are produced by meiosis in sporophytes.

The nuclear structures disappear during
a) Telophase
b) Metaphase 
c) Anaphase
d) Prophase
Correct answer is option 'D'. Can you explain this answer?

Subham Chavan answered
The nuclear envelope and the nucleolus disappear and the spindle fibres start appearing. Metaphase is marked by the alignment of chromosomes at the equatorial plate.

Cell growth results in disturbing the ratio between
  • a)
    Nucleus - chromosome ratio
  • b)
    Cytoplasm-chromosome ratio
  • c)
    Cytoplasm-spindle fibre ratio
  • d)
    Nucleus-cytoplasm ratio
Correct answer is option 'D'. Can you explain this answer?

Anjali Iyer answered
Mitosis usually results in the production of diploid daughter cells with identical genetic complement.
The growth of multicellular organisms is due to mitosis. 
Cell growth results in disturbing the ratio between the nucleus and the cytoplasm. It therefore becomes essential for the cell to divide to restore the nucleo-cytoplasmic ratio.

During which stage of prophase I the crossing over takes place?
  • a)
    Pachytene
  • b)
    Leptotene
  • c)
    Zygotene
  • d)
    Diplotene
Correct answer is option 'A'. Can you explain this answer?

Lakshmi Sarkar answered
The crossing over takes place during the pachytene stage of prophase I of meiosis.

Explanation:
Prophase I is the first stage of meiosis I, which is further divided into five substages: leptotene, zygotene, pachytene, diplotene, and diakinesis. During the prophase I, homologous chromosomes pair up and exchange genetic material through a process known as crossing over. This results in the formation of recombinant chromosomes that carry a combination of genetic material from both parents.

The crossing over occurs during the pachytene stage, which is characterized by the following events:

1. Homologous chromosomes pair up: The homologous chromosomes come together and form a bivalent or a tetrad.

2. Synapsis: The paired homologous chromosomes undergo synapsis, which is the physical association of the homologs.

3. Crossing over: The chromatids of the homologous chromosomes exchange genetic material at specific sites known as chiasmata. This leads to the formation of recombinant chromosomes.

4. Formation of the synaptonemal complex: The synaptonemal complex holds the homologous chromosomes together and facilitates the exchange of genetic material.

5. Nuclear envelope breakdown: The nuclear envelope breaks down, and the spindle fibers attach to the chromosomes.

In conclusion, the crossing over takes place during the pachytene stage of prophase I of meiosis.

 At which stage of mitosis do chromatids separate and pass to different poles?
  • a)
    Anaphase
  • b)
    Telophase
  • c)
    Prophase
  • d)
    Metaphase
Correct answer is option 'A'. Can you explain this answer?

Vijay Bansal answered
Anaphase -The shortest stage of mitosis. The centromeres divide, and the sister chromatids of each chromosome are pulled apart - or 'disjoin' - and move to the opposite ends of the cell, pulled by spindle fibres attached to the kinetochore regions.

Plant Cytokinesis differ from animals Cytokinesis in having
  • a)
    Midbody
  • b)
    Microfilament
  • c)
    Cell plate
  • d)
    None of these
Correct answer is 'C'. Can you explain this answer?

Rohan Singh answered
Plant cells divide by a cell plate that eventually becomes the cell wall whereas animal cells divide by a cleavage furrow.

In plant cells, the new cell wall begins by the
  • a)
    Cell plate
  • b)
    Chromatid
  • c)
    Cell cycle
  • d)
    Centromere
Correct answer is option 'A'. Can you explain this answer?

Sounak Saini answered
The correct answer is option 'A', the cell plate.

Plant cells have a unique feature called the cell wall, which provides support and protection to the cell. During cell division, a new cell wall is formed to separate the two daughter cells. This process is known as cytokinesis.

- Cell Division in Plant Cells:

1. Prophase: In the first stage of cell division, the nuclear membrane starts to disintegrate, and the chromosomes become visible. Each chromosome consists of two identical copies called chromatids, which are held together by a structure called the centromere.

2. Metaphase: The chromosomes align at the center of the cell, forming a metaphase plate. This alignment ensures that each daughter cell receives an equal number of chromosomes during division.

3. Anaphase: The chromatids separate and move towards opposite poles of the cell. This movement is facilitated by the spindle fibers, which attach to the centromere of each chromatid.

4. Telophase: As the chromatids reach the opposite poles, the nuclear membranes start to reform around them. At this stage, the cell begins to prepare for cytokinesis.

- Cytokinesis in Plant Cells:

In animal cells, cytokinesis occurs through a process called cleavage furrow formation, where a contractile ring pinches the cell membrane inwardly. However, plant cells have a rigid cell wall that cannot be constricted in the same way.

1. Cell Plate Formation: Instead of a cleavage furrow, plant cells form a structure called the cell plate during cytokinesis. The cell plate is made up of vesicles containing cell wall materials, such as cellulose and other polysaccharides.

2. Golgi Vesicles: Golgi vesicles containing cell wall materials accumulate at the center of the cell, between the two daughter nuclei.

3. Fusion of Vesicles: The Golgi vesicles fuse together, forming a continuous structure known as the cell plate. This structure gradually expands towards the periphery of the cell, eventually reaching the cell membrane.

4. Cell Wall Deposition: Enzymes are secreted into the cell plate, which catalyze the deposition of cellulose and other components of the cell wall. As the cell plate expands and fuses with the existing cell wall, it forms a new cell wall between the two daughter cells, separating them completely.

In conclusion, the new cell wall in plant cells begins to form through the process of cytokinesis, specifically through the formation and expansion of the cell plate. The Golgi vesicles fuse together to create the cell plate, which then undergoes cell wall deposition to form a new cell wall between the daughter cells.

During mitosis ER and nucleolus begin to disappear at
  • a)
    Early metaphase
  • b)
    Late metaphase
  • c)
    Early prophase 
  • d)
    Late prophase
Correct answer is option 'C'. Can you explain this answer?

Nishanth Singh answered
During mitosis, Endoplasmic Reticulum (ER) and nucleolus begin to disappear at early prophase and these are not observed in late prophase. 

Plant mitosis is generally controlled by
  • a)
    Cytokinin
  • b)
    Genetic make-up
  • c)
    Cytochrome
  • d)
    Auxin
Correct answer is option 'A'. Can you explain this answer?

In plant cell, mitosis cell division is generally controlled by cytokinin hormone. Auxinis also required for cell division in plant.

Centromere is required for
  • a)
    Transcription
  • b)
    Cytoplasmic cleavage
  • c)
    Movement of chromosomes towards poles
  • d)
    Crossing over
Correct answer is option 'C'. Can you explain this answer?

Rajat Kapoor answered
Towards the end of prophase (sometimes called prometaphase), the spindle extends between two poles positioned diametrically opposite one another in the cell and the chromosomes migrate toward the center of the spindle. In metaphase, the centromeres of each chromosome are aligned midway across the spindle on a plane called the equatorial plate.

At this time the centromeres are linked to the spindle fibers. Some of the spindle fibers do not form associations with any chromosomes and extend directly from one pole to the other. The centromeres are duplicated so that each chromatid becomes an independent chromosome and is attached to a spindle fiber connected to one of the two poles.

The onset of anaphase is characterized by the movement of the chromosomes toward opposite poles of the spindle. 

In telophase I, which of the following event takes place?
  • a)
    Nuclear membrane disappear.
  • b)
    Nucleolus disappears.
  • c)
    Nuclear membrane and nucleolus disappear.
  • d)
    Reoccurrence of nuclear membrane and nucleolus.
Correct answer is option 'D'. Can you explain this answer?

Rajat Kapoor answered
The nuclear membrane, also called the nuclear envelope, is a double membrane layer that separates the contents of the nucleus from the rest of the cell. It is found in both animal and plant cells. A cell has many jobs, such as building proteins, converting molecules into energy, and removing waste products. The nuclear envelope protects the cell’s genetic material from the chemical reactions that take place outside the nucleus. It also contains many proteins that are used in organizing DNA and regulating genes.

 In a cell cycle, during which phase are chromosomes arranged on the equatorial plate?
  • a)
    Metaphase
  • b)
    Prophase
  • c)
    Anaphase
  • d)
    Telophase
Correct answer is option 'A'. Can you explain this answer?

Rohan Singh answered
During metaphase, the chromosomes get arranged in the form of a plate called the equatorial plate or metaphase plate at the equator of the spindle. This plate is at right angles to the axis of the spindle and is formed of the kinetochores, the arms of chromatids trailing away. The centromeres are drawn to the equator by the equal pull of two chromosomal fibres which connect the sister kinetochores to the opposite poles. The process of drawing the chromosomes onto the equator of the spindle is known as congression.

Astral body are formed of
  • a)
    Microtubules
  • b)
    Intermediate filaments
  • c)
    Microfilaments
  • d)
    Microvilli
Correct answer is option 'A'. Can you explain this answer?

Diya Datta answered
Astral body are formed of microtubules. Astral bodies are produced by centriole during cell division and attach with centromere of the chromosome.

Cell division is initiated in plants by
  • a)
    Cytokinin
  • b)
    Abscisic acid
  • c)
    Gibberellin
  • d)
    Auxin
Correct answer is option 'A'. Can you explain this answer?

Rahul Bansal answered
Mitosis is the mechanism by which the chromosome content of a somatic cell (haploid or diploid) is kept constant through successive cell divisions. The division of the cell is initiated by division of the nucleus i.e. Karyokinesis followed by division of cytoplasm i.e. Cytokinesis.

Crossing over results in the exchange of genetic material, which occurs between:
  • a)
    Bivalents
  • b)
    Sister chromatids
  • c)
    Non-homologous chromosome
  • d)
    Non-sister chromatids of the homologous chromosomes
Correct answer is option 'D'. Can you explain this answer?

Ayush Joshi answered
Crossing over occurs between prophase 1 and metaphase 1 and is the process where homologous chromosomes pair up with each other and exchange different segments of their genetic material to form recombinant chromosomes. It can also happen during mitotic division, which may result in loss of heterozygosity.

In animal cells, Cytokinesis takes place by furrow deepening centripetally and formation of two daughter cells. This method is known as
  • a)
    Phragmoplast
  • b)
    Cleavage Cytokinesis
  • c)
    Cell plate formation
  • d)
    None of these
Correct answer is option 'B'. Can you explain this answer?

1)Microfilaments collect in the middle region of the cell below the cell membrane. The furrow deepens centripetally and cleaves the cell into two daughter cells. This method is called cleavage cytokinesis. 2)Cytokinesis in plants occurs by cell plate formation. 3)The phragmoplast is a plant cell specific structure that forms during late cytokinesis. Hope it helps!!!!!

Which of the following phases in mitosis is in correct order?
  • a)
    Prophase,telophase,metaphase,anaphase
  • b)
    Prophase ,metaphase,anaphase, telophase
  • c)
    Anaphase,telophase,metaphase,prophase.
  • d)
    Metaphase,prophase,anaphase,telophase
Correct answer is option 'B'. Can you explain this answer?

Shraddha answered
As we know, Prophase is associated with condensation of chromosomes, Metaphase is associated with the arrangement of Chromosomes as Metaphase plate, Anaphase is associated with the separation of chromosomes whereas Telophase is associated with the movement of chromosomes to their respective poles and reformation of cell organelles

In which stage, the cells remain metabolically active but do not proliferate?
  • a)
    G1-phase
  • b)
    G2-phase
  • c)
    Go-phase
  • d)
    S-phase
Correct answer is option 'C'. Can you explain this answer?

Rajat Kapoor answered
Go phase is an inactive phase, also called as quiescent phase of the cell cycle. Cells in Go stage remain me tabolically active but do not proliferate unless called to do so depending on the requirements of the organism.

Synapsis occurs between
  • a)
    A male and female gametes
  • b)
    Ribosome and m-RNA
  • c)
    Spindle fibres and centromeres
  • d)
    Two homologous chromosomes
Correct answer is option 'D'. Can you explain this answer?

Shalini Saha answered
Synapsis occur between two homologous chromosome during zygotene phase of prophase of meiosis I due to presence of synaptical complex between homologous chromosomes.

If the DNA content of an onion tip cell is 2C at the end of the M-phase, what would be its DNA content at the end of the S-phase?
  • a)
    C
  • b)
    2C
  • c)
    3C
  • d)
    4C
Correct answer is option 'D'. Can you explain this answer?

Rithika Bajaj answered
Explanation:

Given: DNA content of an onion tip cell is 2C at the end of the M-phase.

During S-phase:
- The DNA content of a cell doubles during the S-phase.
- The DNA content of a cell at the end of the S-phase can be calculated by multiplying the DNA content at the end of the M-phase by 2.

Calculation:
- DNA content at the end of the S-phase = 2C x 2 = 4C
Therefore, the DNA content of an onion tip cell at the end of the S-phase would be 4C.

Which is the longest phase of the cell cycle?
  • a)
    M-phase
  • b)
    Interphase
  • c)
    Leptotene
  • d)
    S-phase
Correct answer is option 'B'. Can you explain this answer?

Cell cycle is divided into 2 phase. (i) Interphase (a period of preparation for cell division), (ii) M phase (the actual period of cell division). The interphase cell is metabolically quite active. Interphase is the long non dividing phase further divided into G1, S and G2. It occupies 75 to 90 % of entire cell division time.

“The synaptonemal complex is formed during A stage and dissolves during B stage”.
Complete the above statement by choosing the correct option for A and B.
  • a)
    A - Diplotene, B - Diakinesis
  • b)
    A - Leptotene, B - Zygotene
  • c)
    A - Zygotene, B - Diplotene
  • d)
    A - Pachytene, B - Diplotene
Correct answer is option 'D'. Can you explain this answer?

Maheshwar Iyer answered
The Synaptonemal Complex in Meiosis
The synaptonemal complex (SC) is a crucial structure in meiosis that facilitates the pairing of homologous chromosomes. Understanding its formation and dissolution is essential for grasping the process of genetic recombination.
Stages of Meiosis
- Leptotene: Chromosomes begin to condense.
- Zygotene: Homologous chromosomes start to pair, and the synaptonemal complex forms, facilitating close alignment.
- Pachytene: The SC is fully developed, and crossing over occurs.
- Diplotene: The SC begins to dissolve, and homologous chromosomes start to separate.
- Diakinesis: The chromosomes condense further, and the nuclear envelope breaks down.
Explanation of the Correct Answer (Option D)
- A - Pachytene:
- The synaptonemal complex is fully formed during this stage.
- This is when homologous chromosomes are tightly paired, allowing for genetic exchange (crossing over) to occur.
- B - Diplotene:
- The SC begins to dissolve during diplotene.
- Homologous chromosomes start to separate, and the complex is no longer needed for chromosome alignment.
Importance of the Synaptonemal Complex
- The SC is vital for ensuring accurate chromosome pairing and exchange of genetic material.
- Its formation and dissolution are integral to the proper progression of meiosis, leading to genetic diversity in gametes.
In conclusion, the synaptonemal complex is formed during the pachytene stage and dissolves during the diplotene stage, making option D the correct answer. Understanding these processes is crucial for comprehending meiosis and its role in reproduction and genetics.

Various phases of cell cycle are controlled by proteins
  • a)
    Hormones and CDKs
  • b)
    Cytokines and Cyclins
  • c)
    Cyclins and CDKs
  • d)
    Hormones and Cyclins
Correct answer is option 'C'. Can you explain this answer?

Cyclin and CDKs enzymes are involved in controlling various phases of the cell cycle.
Cyclins are among the most important core cell cycle regulators.Cyclin A regulates the progression of cell cycle at S/G2 boundary and G2/M boundary.
 M-phase promoting factor is Cyclin B which regulates the progression of cell cycle at G2/M boundary.
Cyclin D  regulates the progression of cell cycle at G1/S boundary.

CDKs can modify various protein substrates involved in cell cycle progression.
CDK or cyclin dependent kinases are the enzymes that regulate the cell cycle by phosphorylating the amino acids like serine and threonine.

The resting phase is otherwise called as
  • a)
    Prophase
  • b)
    Interphase
  • c)
    Metaphase
  • d)
    Telophase
Correct answer is option 'B'. Can you explain this answer?

Raghav Khanna answered
The interphase, though called the resting phase, is the time during which the cell is preparing for divisionby undergoing both cell growth and DNA replication in an orderly manner.

Which of these processes ensure the haploid phase of life cycle?
  • a)
    Fission
  • b)
    Mitosis
  • c)
    Meiosis
  • d)
    Fertilization
Correct answer is option 'C'. Can you explain this answer?

  • The haploid phase of life cycle occurs when the total chromosome number inside the cell is reduced to half.
  • It occurs by the process of meiosis.
  • Fertilization restores the diploid phase of life cycle.

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