Division of nucleus without being followed by cytokinesis results in a multinucleate condition. Let's understand this in detail:

Nucleus Division:
Nucleus division is the process by which a cell's nucleus divides into two daughter nuclei. This process is known as karyokinesis and is a crucial step during cell division. It involves the separation of the replicated chromosomes into two sets to ensure that each daughter cell receives a complete set of genetic material.

Cytokinesis:
Cytokinesis is the process that follows nucleus division. It involves the division of the cytoplasm, leading to the formation of two daughter cells. During cytokinesis, a contractile ring made up of actin and myosin proteins forms and contracts, causing the plasma membrane to pinch inward, eventually leading to the separation of the two daughter cells.

Multinucleate Condition:
When nucleus division occurs without being followed by cytokinesis, it results in a multinucleate condition. In this condition, the daughter nuclei formed during nucleus division remain within a single cell instead of being distributed into separate cells. As a result, the cell contains multiple nuclei instead of the usual single nucleus.

Importance of Cytokinesis:
Cytokinesis is a crucial step in cell division as it ensures that each daughter cell receives a complete set of genetic material and other cellular components necessary for their functioning. Without cytokinesis, the daughter nuclei would remain within a single cell, leading to an abnormal multinucleate condition.

Significance of a Multinucleate Condition:
In some cases, a multinucleate condition can be observed naturally in certain cell types, such as muscle cells and some fungal hyphae. These cells require multiple nuclei to support their specific functions, such as muscle contraction or efficient nutrient distribution in fungi.

However, in most cases, a multinucleate condition is abnormal and can be indicative of underlying health issues or cellular dysfunctions. It may result from errors during cell division or failure of cytokinesis. Multinucleate cells often exhibit impaired cellular functions and may contribute to the development of various diseases.

In conclusion, division of the nucleus without being followed by cytokinesis results in a multinucleate condition. This condition can have both natural and abnormal occurrences, with implications for cellular function and health.