Which of the following events does not occur inrough endoplasmic retic...
The Rough Endoplasmic Reticulum (RER) is a type of endoplasmic reticulum that is studded with ribosomes on its surface. These ribosomes are responsible for the synthesis of proteins that are destined for secretion, membrane-bound proteins, and proteins for the lysosome. The RER plays a crucial role in protein synthesis, folding, and modification.
The events that occur in the RER are as follows:
1. Protein synthesis: The ribosomes on the surface of the RER synthesize proteins using the genetic code present in the mRNA.
2. Protein folding: The newly synthesized proteins are transported into the lumen of the RER, where they undergo proper folding and attain their native conformation.
3. Protein glycosylation: The proteins are modified by the addition of sugar residues, which are important for their stability and function.
4. Cleavage of signal peptide: The proteins that are destined for secretion or membrane-bound proteins have a signal peptide at their N-terminus. This signal peptide is cleaved off by signal peptidases present in the RER.
5. Quality control: The RER also performs quality control checks on the newly synthesized proteins. Misfolded proteins are recognized and degraded by the proteasome.
6. Transport: The properly folded and modified proteins are transported to the Golgi apparatus for further modification and sorting.
Phospholipid synthesis, on the other hand, occurs in the smooth endoplasmic reticulum (SER). The SER lacks ribosomes on its surface and is responsible for the synthesis of lipids, including phospholipids. Therefore, the correct answer is option D, which states that phospholipid synthesis does not occur in the RER.
Which of the following events does not occur inrough endoplasmic retic...
Rough endoplasmic reticulum is specially meant for protein synthesis bcoz of presence of ribosomes and smooth endoplasmic reticulum is for lipid synthesis due to lack of ribosomes. It is clearly mentioned in ncert