Consider the following statements:1. Progeria is the genetic disease a...
Progeria or Hutchinson-Gilford progeria syndrome is a genetic disease with a defect in the gene LMNA, in which the ageing process is manifested at a very early age and the progeric children typically live to their mid-teens to early twenty.
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Consider the following statements:1. Progeria is the genetic disease a...
Understanding Progeria
Progeria, also known as Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare genetic disorder that causes children to age rapidly. Let's analyze the given statements to understand their accuracy.
Statement 1: Progeria is the genetic disease associated with fast ageing.
- This statement is correct. Progeria is indeed a genetic condition caused by a mutation in the LMNA gene, which leads to accelerated aging in affected individuals.
- Patients with Progeria exhibit symptoms associated with aging, such as hair loss, joint stiffness, and cardiovascular issues, at a very young age.
Statement 2: Progeric patients never live beyond early years of 5 or 6.
- This statement is incorrect. While it's true that Progeria significantly reduces life expectancy, many patients can live into their teens or even early twenties. The average life expectancy is around 13 years, though some have lived longer.
Conclusion
- Based on the analysis, only the first statement is true. Therefore, the correct answer is option A: 1 only.
Understanding Progeria helps shed light on the genetic factors influencing aging and the importance of ongoing research to improve the quality of life for those affected by this condition.