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During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called?
[2005]
- a)AAAT box
- b)TATA box
- c)GGTT box
- d)CAAT box
Correct answer is option 'B'. Can you explain this answer?
Verified Answer
During transcription holoenzyme RNA polymerase binds to a DNA sequence...
About 28 base pairs from transcription start site are TATA boxes. After 40 bases from TATA boxes appears LAAT boxes. Both of these sequence serve as recognition site in Eukaryotic promoters (Transcription in eukaryotic genes in a far more complicated process than in prokaryotes)
Most Upvoted Answer
During transcription holoenzyme RNA polymerase binds to a DNA sequence...
Introduction:
In molecular biology, AUG is a codon that plays a crucial role in protein synthesis. The information carried by AUG is significant for the initiation of translation, and it is also responsible for coding the amino acid methionine. This question asks which statements about AUG are true.
Explanation:
To determine the correct answer, let's evaluate each option one by one:
a) It codes for methionine only:
This statement is incorrect. AUG codes for methionine, but it can also serve as a start codon for protein synthesis. In some cases, AUG can be used to code for methionine within the middle of a protein sequence, but its primary function is as an initiation codon.
b) It is an initiation codon:
This statement is correct. AUG is the most common initiation codon used to start protein synthesis. When an mRNA molecule is translated into a protein, the ribosome recognizes AUG as the start codon and begins the translation process from that point.
c) It codes for methionine in both prokaryotes and eukaryotes:
This statement is correct. The genetic code is nearly universal, meaning that the same codons code for the same amino acids across different organisms. AUG consistently codes for methionine in both prokaryotes (bacteria) and eukaryotes (organisms with a distinct nucleus).
d) All of the above:
This statement is correct. Option D includes all the true statements mentioned above. AUG codes for methionine, serves as an initiation codon, and codes for methionine in both prokaryotes and eukaryotes. Therefore, option D is the correct answer.
Conclusion:
In summary, AUG is an important codon in protein synthesis. It codes for methionine, serves as an initiation codon, and is conserved across different organisms. Therefore, option D, "All of the above," is the correct answer.
In molecular biology, AUG is a codon that plays a crucial role in protein synthesis. The information carried by AUG is significant for the initiation of translation, and it is also responsible for coding the amino acid methionine. This question asks which statements about AUG are true.
Explanation:
To determine the correct answer, let's evaluate each option one by one:
a) It codes for methionine only:
This statement is incorrect. AUG codes for methionine, but it can also serve as a start codon for protein synthesis. In some cases, AUG can be used to code for methionine within the middle of a protein sequence, but its primary function is as an initiation codon.
b) It is an initiation codon:
This statement is correct. AUG is the most common initiation codon used to start protein synthesis. When an mRNA molecule is translated into a protein, the ribosome recognizes AUG as the start codon and begins the translation process from that point.
c) It codes for methionine in both prokaryotes and eukaryotes:
This statement is correct. The genetic code is nearly universal, meaning that the same codons code for the same amino acids across different organisms. AUG consistently codes for methionine in both prokaryotes (bacteria) and eukaryotes (organisms with a distinct nucleus).
d) All of the above:
This statement is correct. Option D includes all the true statements mentioned above. AUG codes for methionine, serves as an initiation codon, and codes for methionine in both prokaryotes and eukaryotes. Therefore, option D is the correct answer.
Conclusion:
In summary, AUG is an important codon in protein synthesis. It codes for methionine, serves as an initiation codon, and is conserved across different organisms. Therefore, option D, "All of the above," is the correct answer.
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