Which one of the following is a wrong statement regarding mutations?[2...
Change in single base pair of DNA is also a type of mutations called point mutations. It is a type of mutation that causes the replacement of a single base nucleotide with another nucleotide of the genetic material, DNA or RNA. For example, a point mutation is the cause of sickle cell disease.
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Which one of the following is a wrong statement regarding mutations?[2...
Change in a single base pair of DNA does not cause mutation:
Mutation is a change in the DNA sequence that can lead to genetic variations. While it is true that mutations can be caused by a variety of factors, including UV and Gamma rays, deletion and insertion of base pairs, and chromosomal aberrations, it is incorrect to say that a change in a single base pair of DNA does not cause a mutation.
Explanation:
- A change in a single base pair of DNA is known as a point mutation.
- Point mutations can have various effects on the resulting protein encoded by the DNA sequence.
- For example, a point mutation can lead to a silent mutation (no change in the amino acid sequence), a missense mutation (change in one amino acid), or a nonsense mutation (introduction of a premature stop codon).
- These changes can ultimately affect the structure and function of the protein, leading to potential phenotypic changes.
- Therefore, it is important to recognize that even a small change in a single base pair of DNA can indeed cause a mutation.