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Sertoli cells are regulated by the pituitary hormone known as [2006]
  • a)
    GH
  • b)
    Prolactin
  • c)
    LH
  • d)
    FSH
Correct answer is option 'D'. Can you explain this answer?
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Sertoli cells are regulated by the pituitary hormone known as [2006]a)...
During spermatogenetic developments spermatids get nourished by nurse or sertoli cells. The function of sertoli cells and hence the spermatogenesis is under the direct influence of folliclestimulating hormone (FSH) secreted by adenohypophyses of pituitary gland.
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Sertoli cells are regulated by the pituitary hormone known as [2006]a)...
Sertoli cells are the cells that line the seminiferous tubules in the testis. These cells protect the spermatids and convey nutrients to both the developing and mature spermatozoa. Sertoli cells are regulated by FSH (Follicle Stimulating Hormone)which is secreted by the anterior pituitary. FSH stimulates Sertoli cells to produce androgen-binding protein and inhibin and together with testosterone, promotes the proliferation of Sertoli cells. So, the correct answer is option 'D'.
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Sertoli cells are regulated by the pituitary hormone known as [2006]a)...
Sertoli cells regulation by FSH
Sertoli cells, which are found in the seminiferous tubules of the testes, play a crucial role in sperm production. These cells are regulated by the pituitary hormone known as Follicle-Stimulating Hormone (FSH).

FSH stimulation of Sertoli cells
- FSH binds to receptors on the surface of Sertoli cells.
- This binding triggers a series of intracellular signaling pathways within the Sertoli cells.
- These pathways ultimately lead to the activation of genes involved in spermatogenesis, the process of sperm production.

Role of Sertoli cells in spermatogenesis
- Sertoli cells provide physical and nutritional support to developing sperm cells.
- They also create the blood-testis barrier, which protects developing sperm from the immune system.
- Additionally, Sertoli cells produce various growth factors and hormones that are necessary for sperm maturation.

Importance of FSH in male reproductive health
- FSH is essential for the proper functioning of the male reproductive system.
- Inadequate FSH levels can lead to impaired spermatogenesis and infertility.
- By regulating Sertoli cells, FSH ensures the continuous production of mature, healthy sperm cells.
In conclusion, Sertoli cells are regulated by the pituitary hormone FSH, which plays a crucial role in spermatogenesis and male reproductive health.
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