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Blood group type A antigen is a complex oligosaccharide which differs from H antigen present in type O individuals by the presence of terminal
- a)Glucose
- b)Galactose
- c)N-acetylgalactosamine
- d)Fucose
Correct answer is option 'C'. Can you explain this answer?
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Blood group type A antigen is a complex oligosaccharide which differs ...
IA and IB alleles in human encode glycosyl transferase enzyme, each causing different modification in the terminal sugar of the H-structure (carbohydrate group) present on the surface of RBC. Addition of terminal N- acetylgalactosamine to the H-structure by IA allele results in A antigen and addition of terminal galactose by IB forms B antigen in human RBC, which is absent in the O type individuals.
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Blood group type A antigen is a complex oligosaccharide which differs ...
Blood group antigens are molecules found on the surface of red blood cells. These antigens determine an individual's blood type. The ABO blood group system is one of the most well-known and important blood group systems, which classifies blood into four types: A, B, AB, and O. The A antigen, present in individuals with blood type A, is a complex oligosaccharide that differs from the H antigen found in type O individuals.
The H antigen is the precursor antigen that is present in all individuals regardless of their blood type. It serves as the foundation for the A and B antigens. The A antigen is formed by the addition of a specific sugar residue to the H antigen structure. In the case of blood type A, this specific sugar residue is N-acetylgalactosamine (GalNAc).
To understand why the correct answer is N-acetylgalactosamine (GalNAc), let's consider the other options:
a) Glucose: Glucose is a simple sugar that is not involved in the formation of the A antigen. While glucose is a component of various biological molecules, it is not directly responsible for the difference between the A and H antigens.
b) Galactose: Galactose is another simple sugar that is also not directly involved in the formation of the A antigen. While galactose is present in other blood group antigens, it does not differentiate between the A and H antigens.
c) N-acetylgalactosamine (GalNAc): This is the correct answer. The A antigen differs from the H antigen by the presence of GalNAc as a terminal sugar residue. The addition of GalNAc to the H antigen structure results in the formation of the A antigen in individuals with blood type A.
d) Fucose: Fucose is a sugar that is also not directly involved in the formation of the A antigen. While fucose is present in other blood group antigens, it does not differentiate between the A and H antigens.
In summary, the A antigen found in individuals with blood type A differs from the H antigen found in type O individuals by the presence of N-acetylgalactosamine (GalNAc) as a terminal sugar residue. This difference in sugar composition is responsible for the distinction between blood type A and type O in the ABO blood group system.
The H antigen is the precursor antigen that is present in all individuals regardless of their blood type. It serves as the foundation for the A and B antigens. The A antigen is formed by the addition of a specific sugar residue to the H antigen structure. In the case of blood type A, this specific sugar residue is N-acetylgalactosamine (GalNAc).
To understand why the correct answer is N-acetylgalactosamine (GalNAc), let's consider the other options:
a) Glucose: Glucose is a simple sugar that is not involved in the formation of the A antigen. While glucose is a component of various biological molecules, it is not directly responsible for the difference between the A and H antigens.
b) Galactose: Galactose is another simple sugar that is also not directly involved in the formation of the A antigen. While galactose is present in other blood group antigens, it does not differentiate between the A and H antigens.
c) N-acetylgalactosamine (GalNAc): This is the correct answer. The A antigen differs from the H antigen by the presence of GalNAc as a terminal sugar residue. The addition of GalNAc to the H antigen structure results in the formation of the A antigen in individuals with blood type A.
d) Fucose: Fucose is a sugar that is also not directly involved in the formation of the A antigen. While fucose is present in other blood group antigens, it does not differentiate between the A and H antigens.
In summary, the A antigen found in individuals with blood type A differs from the H antigen found in type O individuals by the presence of N-acetylgalactosamine (GalNAc) as a terminal sugar residue. This difference in sugar composition is responsible for the distinction between blood type A and type O in the ABO blood group system.
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Blood group type A antigen is a complex oligosaccharide which differs from H antigen present in type O individuals by the presence of terminala)Glucoseb)Galactosec)N-acetylgalactosamined)FucoseCorrect answer is option 'C'. Can you explain this answer?
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