Haemophilia is more common in males because it is aa)Recessive character carried by Y chromosomeb)Dominant character carried byY chromosomec)Dominant trait carried by X chromosomed)Recessive trait carried by X chromosomeCorrect answer is option 'D'. Can you explain this answer?

Question

Answer

As a recessive X-linked genetic disorder, the mutation that causes hemophilia is passed to offspring via the X chromosome. Hemophilia is more common among male children because they only inherit one X chromosome. Humans have 22 pairs of autosomal chromosomes and one pair of sex chromosomes, making a total of 46 chromosomes in each cell. In males, there is both an X chromosome and a Y chromosome, whereas females have two X chromosomes. Male offspring inherit their X chromosome from their mother and their Y chromosome from their father, while female offspring inherit an X chromosome from each parent. Since males only have one X chromosome, they will develop symptoms of hemophilia if that chromosome carries the mutation. However, because the condition is recessive, the inheritance of one abnormal X chromosome does not usually cause symptoms in females because they usually also inherit another normal X chromosome. These females are then classified as carriers of the disease and can pass on the mutation to male offspring even though they do not develop symptoms themselves. Technically, a female can develop hemophilia if she is born to a female carrier and a man affected by hemophilia, but this is very rare

Answer

As a recessive X-linked genetic disorder, the mutation that causes hemophilia is passed to offspring via the X chromosome. Hemophilia is more common among male children because they only inherit one X chromosome. In males, there is both an X chromosome and a Y chromosome, whereas females have two X chromosomes.

Answer

Reason why Haemophilia is more common in males:
Haemophilia is a genetic disorder that affects the blood's ability to clot. It is caused by a mutation in one of the genes that provides instructions for making proteins needed to form blood clots. In the case of haemophilia, this mutation affects one of the genes on the X chromosome.

Recessive trait carried by X chromosome:
- The gene responsible for haemophilia is located on the X chromosome. Males have one X chromosome and one Y chromosome, while females have two X chromosomes.
- Since haemophilia is a recessive trait, a female would need to inherit two copies of the mutated gene (one from each parent) to have the disorder. This is less likely to occur because females have two X chromosomes and would need to inherit the mutated gene on both of them.
- On the other hand, males only have one X chromosome, so if they inherit the mutated gene on their X chromosome, they will have haemophilia.

Conclusion:
Therefore, haemophilia is more common in males because they only need to inherit one copy of the mutated gene on their X chromosome, while females would need to inherit two copies. This is why males are more likely to have haemophilia compared to females.

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