During blood clotting, fibrin is produced by[MP PMT 2000]a)Thrombokinaseb)Prothrombinc)Liverd)ProteolysisCorrect answer is option 'B'. Can you explain this answer?

Question

Answer

Thrombin converts fibrinogen into fibrin
the inactive form of thrombin is prothrombin

Answer

Answer

Fibrin is a tough protein substance that is arranged inlong fibrous chains; it is formed fromfibrinogen, a soluble protein that is produced by the liver and foundin blood plasma. When tissue damage results in bleeding,fibrinogen is converted at the wound into fibrin by the action ofthrombin, a clotting enzyme.

Answer

During blood clotting, fibrin is produced by prothrombin.

Fibrin is a fibrous protein that plays a crucial role in the formation of blood clots. It forms a mesh-like network that traps platelets, red blood cells, and other components of the blood to form a solid clot. This process is essential for preventing excessive bleeding after an injury or during surgery.

The production of fibrin is a complex process involving several steps and clotting factors. One of the key clotting factors involved is prothrombin. Prothrombin is a protein synthesized by the liver and released into the bloodstream.

The production of fibrin from prothrombin occurs through a series of enzymatic reactions known as the coagulation cascade. The coagulation cascade is triggered when there is damage to blood vessels or activation of platelets.

Here is a step-by-step explanation of how fibrin is produced from prothrombin during blood clotting:

1. Activation of the coagulation cascade: When there is damage to blood vessels or activation of platelets, a series of reactions is initiated to activate the coagulation cascade. This cascade involves the sequential activation of clotting factors, including prothrombin.

2. Activation of prothrombin: Prothrombin is converted into its active form, thrombin, through the action of an enzyme called thrombokinase or tissue factor. Thrombokinase is released by damaged tissues or activated platelets.

3. Conversion of fibrinogen to fibrin: Thrombin acts on fibrinogen, another protein present in the blood, and cleaves it into fibrin monomers. These monomers then polymerize to form long chains of fibrin.

4. Formation of a fibrin clot: The fibrin monomers form a mesh-like network that traps platelets, red blood cells, and other components of the blood, forming a clot. This clot helps to seal the damaged blood vessel and prevent further bleeding.

In summary, fibrin is produced from prothrombin during blood clotting. Prothrombin is converted into thrombin, which then acts on fibrinogen to form fibrin. This fibrin forms the structural framework of a blood clot, helping to stop bleeding and promote wound healing.

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