The TCA cycle is named aftera)Robert Emersonb)Melvin Calvinc)Embdend)Hans KrebsCorrect answer is option 'D'. Can you explain this answer?

Question

Answer

*Tricarboxylic acid (TCA) cycle is a series of enzyme-catalyzed chemical reactions used by all aerobic organisms to release the stored energy........ *It is a part of cellular respiration........ *It is also called as citric acid cycle or Krebs cycles which is named after it's discoverer Hans Krebs..... Thus, the correct answer is option 'D'.

Answer

The TCA cycle is also known as the Krebs Cycle named for its discoverer, Hans Adolf Krebs.

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TCA cycle is also know as Krebs cycle and is named after a scientist Hans krebs.

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Hans kreb

Answer

The TCA cycle is named after Hans Krebs.

The TCA cycle, also known as the citric acid cycle or Krebs cycle, is a central metabolic pathway that occurs in the mitochondria of eukaryotic cells. It is named after the British biochemist Hans Krebs, who first described this cycle in the 1930s and 1940s.

Discovery of the TCA Cycle:
Hans Krebs made significant contributions to our understanding of cellular respiration and the TCA cycle. In the early 1930s, he and his colleagues discovered that when tissues were incubated with radioactive glucose, the radioactivity appeared in carbon dioxide. This led to the discovery of the glycolysis pathway.

In the late 1930s, Krebs further investigated the fate of glucose metabolism and discovered that another cycle was responsible for the complete oxidation of glucose. He identified the key intermediates and reactions involved in this cycle, which became known as the TCA cycle or Krebs cycle.

Key Steps and Intermediates:
The TCA cycle is a series of enzymatic reactions that occur in the mitochondrial matrix. It oxidizes acetyl-CoA, a two-carbon molecule derived from carbohydrates, fats, and proteins, to generate energy in the form of ATP. Here are the key steps and intermediates of the TCA cycle:

1. Acetyl-CoA combines with oxaloacetate to form citrate, which is catalyzed by the enzyme citrate synthase.
2. Citrate is then converted to isocitrate by the enzyme aconitase.
3. Isocitrate undergoes oxidative decarboxylation by isocitrate dehydrogenase, producing alpha-ketoglutarate and NADH.
4. Alpha-ketoglutarate is further decarboxylated by alpha-ketoglutarate dehydrogenase, generating another molecule of NADH and succinyl-CoA.
5. Succinyl-CoA is converted to succinate by succinyl-CoA synthetase, generating ATP.
6. Succinate is oxidized by succinate dehydrogenase, producing FADH2 and fumarate.
7. Fumarate is hydrated to malate by fumarase.
8. Malate is oxidized to oxaloacetate by malate dehydrogenase, generating NADH.

Importance of the TCA Cycle:
The TCA cycle is essential for cellular respiration and provides energy for various metabolic processes. It not only generates ATP but also produces reducing equivalents in the form of NADH and FADH2, which are utilized in oxidative phosphorylation to synthesize more ATP.

Furthermore, the TCA cycle also serves as a hub for the interconversion of various metabolites. It provides precursor molecules for the biosynthesis of amino acids, nucleotides, and lipids. Additionally, the intermediates of the TCA cycle can be used for gluconeogenesis, the synthesis of glucose from non-carbohydrate sources.

In conclusion, the TCA cycle is named after Hans Krebs, who elucidated the key steps and intermediates of this metabolic pathway. His groundbreaking work in the field of cellular respiration laid the foundation for our understanding of energy production and metabolism in living organisms.

Answer

The TCA cycle, also known as the Krebs cycle or tricarboxylic acid cycle, has been named after the German biochemist Sir Hans Krebs who discovered the cycle in 1937 in England.

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