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In the context of genetics, what do you understand by RNA interference (RNAi) ?
- a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.
- b)It is a process in which two or more molecules exchange their RNA to perform a specific function.
- c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.
- d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.
Correct answer is option 'D'. Can you explain this answer?
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In the context of genetics, what do you understand by RNA interference...
- The term RNA interference (RNAi) was coined to describe a cellular mechanism that uses the gene’s own DNA sequence of the gene to turn it off, a process that researchers call silencing. In a wide variety of organisms, including animals, plants, and fungi, RNAi is triggered by double-stranded RNA (dsRNA). Hence option (d) is the correct answer.
- During RNAi, long dsRNA is cut or "diced" into small fragments ~21 nucleotides long by an enzyme called "Dicer". These small fragments referred to as small interfering RNAs (siRNA), bind to proteins from a special family: the Argonaute proteins.
- RNAi is widely used by researchers to silence genes in order to learn something about their function. siRNAs can be designed to match any gene, can be manufactured cheaply, and can be readily administered to cells. One can now order commercially synthesized siRNAs to silence virtually any gene in a human or other organism's cell, dramatically accelerating the pace of biomedical research. Furthermore, the ability to turn off the expression of a single gene makes RNAi an appealing therapeutic approach to treat infectious diseases or genetic disorders, such as those that result from the inappropriate and undesirable activity of a gene, as in many cancers and neurodegenerative diseases. There are currently several clinical trials testing the safety and effectiveness of siRNA drugs.
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In the context of genetics, what do you understand by RNA interference (RNAi) ?a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.b)It is a process in which two or more molecules exchange their RNA to perform a specific function.c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.Correct answer is option 'D'. Can you explain this answer?
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In the context of genetics, what do you understand by RNA interference (RNAi) ?a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.b)It is a process in which two or more molecules exchange their RNA to perform a specific function.c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.Correct answer is option 'D'. Can you explain this answer? for UPSC 2025 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about In the context of genetics, what do you understand by RNA interference (RNAi) ?a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.b)It is a process in which two or more molecules exchange their RNA to perform a specific function.c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.Correct answer is option 'D'. Can you explain this answer? covers all topics & solutions for UPSC 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for In the context of genetics, what do you understand by RNA interference (RNAi) ?a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.b)It is a process in which two or more molecules exchange their RNA to perform a specific function.c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.Correct answer is option 'D'. Can you explain this answer?.
In the context of genetics, what do you understand by RNA interference (RNAi) ?a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.b)It is a process in which two or more molecules exchange their RNA to perform a specific function.c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.Correct answer is option 'D'. Can you explain this answer? for UPSC 2025 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about In the context of genetics, what do you understand by RNA interference (RNAi) ?a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.b)It is a process in which two or more molecules exchange their RNA to perform a specific function.c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.Correct answer is option 'D'. Can you explain this answer? covers all topics & solutions for UPSC 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for In the context of genetics, what do you understand by RNA interference (RNAi) ?a)It is a process in which the normal functioning of an RNA is altered by replacing its uracil nucleotide with thymine.b)It is a process in which two or more molecules exchange their RNA to perform a specific function.c)It is the insertion or removal of molecules into a solid host without a major disruption of the structure.d)It is a biological process in which genetic expression is inhibited by silencing specific mRNA.Correct answer is option 'D'. Can you explain this answer?.
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