Which of these statements is false regarding myasthenia gravis?a)It af...
Myasthenia gravis is not a genetic disease. Rather, it is an autoimmune disorder which affects neuromuscular junctions. It leads to fatigue, muscle weakness and paralysis of skeletal muscles.
Which of these statements is false regarding myasthenia gravis?a)It af...
Myasthenia Gravis Overview
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. Understanding its nature helps clarify why option B is false.
Key Characteristics of Myasthenia Gravis
- Affects Neuromuscular Junctions: MG disrupts communication between nerves and muscles. The immune system mistakenly attacks acetylcholine receptors at the neuromuscular junction, leading to muscle weakness.
- Results in Fatigue: Patients experience muscle fatigue that worsens with activity and improves with rest. This fatigue is a hallmark symptom of the disease.
- Leads to Paralysis of Skeletal Muscles: While MG does not cause paralysis in the traditional sense, it can severely weaken skeletal muscles, affecting activities like chewing, swallowing, and even breathing in severe cases.
Why Option B is False
- Not a Genetic Disease: Myasthenia gravis is primarily an autoimmune condition, meaning it arises from the immune system's abnormal response rather than a genetic mutation. While some genetic predisposition may exist, MG is not classified as a genetic disease like muscular dystrophy or cystic fibrosis. Environmental factors and autoimmunity play larger roles in its onset.
Conclusion
In summary, while myasthenia gravis affects muscle function and leads to fatigue and weakness, it is not a genetic disease, making option B the false statement among the given choices. Understanding this distinction is crucial for effective diagnosis and management of the disorder.