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Which of these disorders lead to degeneration of skeletal muscles?
  • a)
    Muscular dystrophy
  • b)
    Gout
  • c)
    Tetany
  • d)
    Osteoporosis
Correct answer is option 'A'. Can you explain this answer?
Most Upvoted Answer
Which of these disorders lead to degeneration of skeletal muscles?a)Mu...
Muscular dystrophy is a genetic disorder of the muscular system. It leads to the progressive degeneration of skeletal muscles and loss of muscle mass. The life span of patients is often shortened.
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Which of these disorders lead to degeneration of skeletal muscles?a)Mu...
Understanding Muscular Dystrophy
Muscular dystrophy (MD) is a group of genetic disorders characterized by the progressive degeneration and weakness of skeletal muscles. Here’s how it leads to muscle degeneration:
Genetic Basis
- MD is caused by mutations in genes responsible for muscle structure and function.
- The most common type, Duchenne muscular dystrophy, is linked to the dystrophin gene on the X chromosome.
Molecular Impact
- The absence of essential proteins leads to muscle fiber damage.
- Muscle fibers are replaced by fat and connective tissue, which impairs function.
Symptoms and Progression
- Early symptoms include difficulty walking, frequent falls, and trouble with motor skills.
- As the disorder progresses, muscle weakness can lead to the inability to perform daily activities.
Comparison with Other Disorders
- Gout primarily affects joints and does not cause muscle degeneration.
- Tetany involves muscle spasms but is not characterized by muscle degeneration.
- Osteoporosis affects bone density and health, with no direct impact on skeletal muscles.
Conclusion
In summary, muscular dystrophy is the only disorder among the options listed that specifically leads to the degeneration of skeletal muscles. Understanding this condition is crucial for identifying its impact on mobility and overall health in affected individuals.
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