Answer:

Introduction:
In genetics, an allele is one of the possible forms of a gene that is present at a specific location on a chromosome. Each individual inherits two alleles for a particular gene, one from each parent. These alleles can be the same (homozygous) or different (heterozygous).

Explanation:
The question states that the total sum of all the frequencies of the allele is one (option 'A'). This statement indicates that the frequencies of all the alleles in a population add up to 100% or 1.

Understanding Allele Frequencies:
Allele frequencies are a measure of how common a particular allele is in a population. They are expressed as proportions or percentages, and they represent the relative abundance of each allele within the population.

Example:
Let's consider a population of 100 individuals where a particular gene has two alleles, A and a. If 70 individuals have the genotype AA, 20 individuals have the genotype Aa, and 10 individuals have the genotype aa, we can calculate the allele frequencies.

- Number of copies of allele A = 2 * (70 + 20) = 180
- Number of copies of allele a = 2 * (20 + 10) = 60

To find the frequencies, we divide the number of copies of each allele by the total number of alleles in the population.

- Frequency of allele A = 180 / (180 + 60) = 0.75 or 75%
- Frequency of allele a = 60 / (180 + 60) = 0.25 or 25%

The sum of these frequencies is 0.75 + 0.25 = 1 or 100%.

Conclusion:
In genetics, the sum of all the frequencies of the allele in a population is always one (100%). This is because each individual has two alleles for a particular gene, and the frequencies represent the relative abundance of these alleles in the population.