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During DNA replication, Okazaki fragments are used to elongate [2017]
- a)The lagging strand towards replication fork
- b)The leading strand away from replication fork
- c)The lagging strand away from the replication fork
- d)The leading strand towards replication fork.
Correct answer is option 'C'. Can you explain this answer?
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During DNA replication, Okazaki fragments are used to elongate [2017]...
Lagging strand is a replicated strand 0f DNA which is formed in short segments called Okazaki fragments. Its growth is discontinuous. The direction of growth of the lagging strand is 3' → 5’ though in each Okazaki fragment it is 5’ → 3’.
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During DNA replication, Okazaki fragments are used to elongate [2017]...
Okazaki fragments in DNA replication
Okazaki fragments are short, newly synthesized DNA fragments that are formed on the lagging strand during DNA replication. They are essential for the replication of the lagging strand, which is synthesized discontinuously in the opposite direction of the replication fork.
Role of Okazaki fragments
- Okazaki fragments are used to elongate the lagging strand away from the replication fork.
- The lagging strand is synthesized in short, discontinuous fragments because DNA polymerase can only synthesize DNA in the 5' to 3' direction.
- As the replication fork opens and the DNA unwinds, primase generates RNA primers on the lagging strand.
- DNA polymerase then synthesizes short DNA fragments in the 5' to 3' direction away from the replication fork.
- These fragments are Okazaki fragments, which are later joined together by DNA ligase to form a continuous strand.
Significance of Okazaki fragments
- Okazaki fragments ensure that the lagging strand is synthesized efficiently and accurately during DNA replication.
- Without Okazaki fragments, the lagging strand would not be able to replicate properly, leading to errors and incomplete DNA synthesis.
- The presence of Okazaki fragments allows for the coordinated and accurate replication of both the leading and lagging strands in DNA replication.
In conclusion, Okazaki fragments play a crucial role in the replication of the lagging strand by elongating it away from the replication fork in a discontinuous manner. Their formation and subsequent joining together ensure the accurate and efficient replication of DNA.
Okazaki fragments are short, newly synthesized DNA fragments that are formed on the lagging strand during DNA replication. They are essential for the replication of the lagging strand, which is synthesized discontinuously in the opposite direction of the replication fork.
Role of Okazaki fragments
- Okazaki fragments are used to elongate the lagging strand away from the replication fork.
- The lagging strand is synthesized in short, discontinuous fragments because DNA polymerase can only synthesize DNA in the 5' to 3' direction.
- As the replication fork opens and the DNA unwinds, primase generates RNA primers on the lagging strand.
- DNA polymerase then synthesizes short DNA fragments in the 5' to 3' direction away from the replication fork.
- These fragments are Okazaki fragments, which are later joined together by DNA ligase to form a continuous strand.
Significance of Okazaki fragments
- Okazaki fragments ensure that the lagging strand is synthesized efficiently and accurately during DNA replication.
- Without Okazaki fragments, the lagging strand would not be able to replicate properly, leading to errors and incomplete DNA synthesis.
- The presence of Okazaki fragments allows for the coordinated and accurate replication of both the leading and lagging strands in DNA replication.
In conclusion, Okazaki fragments play a crucial role in the replication of the lagging strand by elongating it away from the replication fork in a discontinuous manner. Their formation and subsequent joining together ensure the accurate and efficient replication of DNA.
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During DNA replication, Okazaki fragments are used to elongate [2017]a)The lagging strand towards replication forkb)The leading strand away from replication forkc)The lagging strand away from the replication forkd)The leading strand towards replication fork.Correct answer is option 'C'. Can you explain this answer?
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