Option D is incorrect.

• There are many reasons for mutations in the genomic sequence.

• Some of the mutations are inherited whereas others can arise due to the environment or mistake by the DNA polymerase enzymes.

• Mutations arise more frequently due to error of the DNA polymerase. Most of the times, these mutations are detected and repaired.

• Other times. these mutations might arise in the non- coding sequence of the DNA.

Incorrect Statement:
Genes cannot acquire mutations in their sequence.

Explanation:
The statement "Genes cannot acquire mutations in their sequence" is incorrect. Genes can indeed acquire mutations in their sequence. Mutations are changes in the DNA sequence of a gene, and they can occur spontaneously or be induced by external factors such as radiation, chemicals, or errors during DNA replication.

Genes and Nucleotides:
- A gene is a sequence of nucleotides, which are the building blocks of DNA.
- Nucleotides are represented by the letters A, T, C, and G, which stand for adenine, thymine, cytosine, and guanine, respectively.
- Genes are located on chromosomes and contain the instructions for making specific proteins.

Gene Expression:
- During the process of gene expression, DNA is first copied into RNA through a process called transcription.
- This RNA molecule, known as messenger RNA (mRNA), carries the genetic information from the gene to the ribosomes, where protein synthesis occurs.
- The mRNA is then translated into a specific sequence of amino acids, which form a protein.

Mutations in Genes:
- Mutations can occur in genes, leading to changes in the DNA sequence.
- Mutations can be classified into different types, including point mutations (changes in a single nucleotide), insertions (addition of extra nucleotides), deletions (removal of nucleotides), and chromosomal rearrangements.
- Mutations can have different effects on gene function. Some mutations may be harmless, while others can disrupt protein production or alter the function of the protein.
- Mutations can also be inherited from parents or occur spontaneously during DNA replication.

Importance of Mutations:
- Mutations are essential for genetic diversity and evolution.
- They provide the raw material for natural selection, as some mutations may confer advantages in certain environments.
- However, mutations can also be detrimental and lead to genetic disorders or diseases.

Conclusion:
In summary, the statement that "Genes cannot acquire mutations in their sequence" is incorrect. Genes can acquire mutations, which can have various effects on gene function and can be both beneficial and harmful. Mutations are an important driving force for genetic diversity and evolution.