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Which of the following, is not a factor responsible for maintaining high osmolarity of the renal medulla?
(i) Active transport of salt from the upper region of the ascending limb.
(ii) The spatial arrangement of juxtamedullary nephrons
(iii) Diffusion of urea from the collecting duct.
(iv) Diffusion of salt from the descending limb of the loop of Henle.
  • a)
    Only (i)
  • b)
    Only (iv)
  • c)
    (ii) and (iii)
  • d)
    (i) and (iv)
Correct answer is option 'B'. Can you explain this answer?
Most Upvoted Answer
Which of the following, is not a factor responsible for maintaining hi...
Introduction:
The renal medulla is responsible for the concentration and dilution of urine. It maintains a high osmolarity, which is necessary for the reabsorption of water. Several factors contribute to maintaining the high osmolarity of the renal medulla.

Explanation:
(i) Active transport of salt from the upper region of the ascending limb: This factor contributes to the high osmolarity of the renal medulla. The ascending limb of the loop of Henle actively transports sodium and chloride ions out of the tubular fluid. This creates a concentration gradient that helps in the reabsorption of water in the descending limb.

(ii) The spatial arrangement of juxtamedullary nephrons: This factor also contributes to the high osmolarity of the renal medulla. Juxtamedullary nephrons have longer loops of Henle that extend deeper into the medulla. This allows for a greater concentration of solutes in the interstitial fluid, leading to the maintenance of high osmolarity.

(iii) Diffusion of urea from the collecting duct: This factor contributes to the high osmolarity of the renal medulla. Urea is passively reabsorbed from the collecting ducts into the interstitial fluid. It contributes to the high osmolarity by increasing the concentration of solutes in the medullary interstitial fluid.

(iv) Diffusion of salt from the descending limb of the loop of Henle: This factor does not contribute to the maintenance of high osmolarity. The descending limb of the loop of Henle is permeable to water but not to salt. As a result, salt does not diffuse out of the descending limb and does not contribute to the concentration gradient in the medulla.

Conclusion:
Among the given options, the factor that is not responsible for maintaining the high osmolarity of the renal medulla is the diffusion of salt from the descending limb of the loop of Henle. This is because the descending limb is permeable to water but not to salt, so salt does not contribute to the concentration gradient in the medulla.
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Which of the following, is not a factor responsible for maintaining hi...
Descending limb of loop of Henle is impermeable to salts.
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Which of the following, is not a factor responsible for maintaining high osmolarity of the renal medulla?(i) Active transport of salt from the upper region of the ascending limb.(ii) The spatial arrangement of juxtamedullary nephrons(iii) Diffusion of urea from the collecting duct.(iv) Diffusion of salt from the descending limb of the loop of Henle.a)Only (i)b)Only (iv)c)(ii) and (iii)d)(i) and (iv)Correct answer is option 'B'. Can you explain this answer? for NEET 2025 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Which of the following, is not a factor responsible for maintaining high osmolarity of the renal medulla?(i) Active transport of salt from the upper region of the ascending limb.(ii) The spatial arrangement of juxtamedullary nephrons(iii) Diffusion of urea from the collecting duct.(iv) Diffusion of salt from the descending limb of the loop of Henle.a)Only (i)b)Only (iv)c)(ii) and (iii)d)(i) and (iv)Correct answer is option 'B'. Can you explain this answer? covers all topics & solutions for NEET 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following, is not a factor responsible for maintaining high osmolarity of the renal medulla?(i) Active transport of salt from the upper region of the ascending limb.(ii) The spatial arrangement of juxtamedullary nephrons(iii) Diffusion of urea from the collecting duct.(iv) Diffusion of salt from the descending limb of the loop of Henle.a)Only (i)b)Only (iv)c)(ii) and (iii)d)(i) and (iv)Correct answer is option 'B'. Can you explain this answer?.
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