With reference to the Marburg virus disease (MVD), consider the follow...
Answer:
The correct answer is option 'C', which means both statements 1 and 2 are correct.
Explanation:
Marburg virus disease (MVD) is a severe hemorrhagic fever caused by the Marburg virus, which belongs to the same family as the Ebola virus. Here is a detailed explanation of each statement:
Statement 1: MVD is a severe hemorrhagic fever that affects both people and non-human primates.
This statement is correct. MVD can affect both humans and non-human primates. It was first identified in 1967 when outbreaks occurred simultaneously in Marburg and Frankfurt in Germany, as well as in Belgrade, Serbia. The disease was traced back to African green monkeys (Chlorocebus spp.) that were imported from Uganda for research purposes. Since then, sporadic outbreaks of MVD have been reported in Africa, primarily in Uganda, Angola, and the Democratic Republic of Congo. The virus can cause severe illness with high fever, headache, muscle pain, and internal bleeding. The case fatality rate can be as high as 88%.
Statement 2: It is transmitted to people from fruit bats and spreads among humans through human-to-human transmission.
This statement is also correct. Fruit bats of the Pteropodidae family are considered to be the natural reservoir hosts of the Marburg virus. These bats can carry the virus without being affected by it. The virus can be transmitted to humans through direct contact with the bodily fluids (such as blood, saliva, urine, and feces) of infected bats. The virus can then spread among humans through human-to-human transmission, primarily through direct contact with the blood, secretions, organs, or other bodily fluids of infected individuals. This can occur in healthcare settings, during burial rituals, or through close personal contact.
In conclusion, both statements 1 and 2 are correct as MVD is a severe hemorrhagic fever that affects both people and non-human primates, and it is transmitted to people from fruit bats and spreads among humans through human-to-human transmission.
With reference to the Marburg virus disease (MVD), consider the follow...
The World Health Organization recently said that Equatorial Guinea had confirmed its first-ever outbreak of Marburg disease.
About Marburg virus disease (MVD):
- What is it? MVD, earlier known as Marburg hemorrhagic fever, is a rare but severe hemorrhagic fever that affects both people and non-human primates.
- Causative agent: MVD is caused by the Marburg virus, a genetically unique zoonotic (animal-borne) RNA virus. Marburg and Ebola viruses are both members of the Filoviridae family (filovirus).
- Marburg virus was first recognized in 1967, when outbreaks of hemorrhagic fever occurred simultaneously in laboratories in Marburg and Frankfurt, Germany and in Belgrade, Yugoslavia (now Serbia).
- The reservoir host of the Marburg virus is the African fruit bat, Rousettus aegyptiacus.
- Transmission: The Marburg virus is transmitted to people from fruit bats and spreads among humans through human-to-human transmission.
- Fatality: The average MVD case fatality rate is around 50%.
- Treatment:
- There is no specific treatment for Marburg virus disease.
- Supportive therapy, such as intravenous fluids, electrolyte replacement, supplemental oxygen, as well as blood and blood products replacement, improves survival.
Hence both statements are correct.
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