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What is the primary focus of mitochondrial gene therapy (MGT)?
  • a)
    Modifying genes in reproductive cells
  • b)
    Modifying genes in plants
  • c)
    Modifying mitochondrial DNA
  • d)
    Modifying genes in body cells
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
What is the primary focus of mitochondrial gene therapy (MGT)?a)Modify...
Primary Focus of Mitochondrial Gene Therapy (MGT)
Mitochondrial gene therapy (MGT) primarily focuses on modifying mitochondrial DNA to address various mitochondrial diseases and disorders. This innovative approach targets the genetic material within the mitochondria, the powerhouse of the cell, with the aim of correcting mutations that lead to dysfunctional mitochondria.

Key Points:
- Mitochondrial DNA (mtDNA) is separate from nuclear DNA and is solely inherited from the mother, making it a unique target for gene therapy.
- Mutations in mtDNA can result in a range of mitochondrial disorders, affecting energy production and cellular function.
- MGT involves techniques such as mitochondrial replacement therapy (MRT) or mitochondrial editing to replace or modify defective mitochondrial DNA.
- The goal of MGT is to alleviate symptoms and potentially cure mitochondrial diseases by restoring proper mitochondrial function at the genetic level.
- While still in the experimental stage, MGT holds promise for treating a variety of mitochondrial disorders, offering hope for individuals affected by these conditions.
In conclusion, the primary focus of mitochondrial gene therapy is to correct mutations in mitochondrial DNA, paving the way for new treatment options for mitochondrial diseases.
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Community Answer
What is the primary focus of mitochondrial gene therapy (MGT)?a)Modify...
The primary focus of mitochondrial gene therapy (MGT) is to modify mitochondrial DNA (mtDNA) to address mitochondrial diseases caused by mutations or defects in mtDNA. It involves replacing defective mtDNA with healthy mtDNA from a donor.
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What is the primary focus of mitochondrial gene therapy (MGT)?a)Modifying genes in reproductive cellsb)Modifying genes in plantsc)Modifying mitochondrial DNAd)Modifying genes in body cellsCorrect answer is option 'C'. Can you explain this answer?
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