In the context of hereditary diseases, consider the following statemen...
Mitochondrial Replacement Therapy and Inheritance of Mitochondrial Diseases
Mitochondrial replacement therapy (MRT) is a technique that involves replacing defective mitochondria in an egg or embryo with healthy ones from a donor. This therapy can prevent the transmission of mitochondrial diseases from a mother to her child.
On the other hand, mitochondrial diseases are inherited from the mother and not from the father. This is because the egg contributes most of the cytoplasmic components, including mitochondria, to the developing embryo. The sperm, on the other hand, only contributes its nucleus, which contains the genetic material.
Therefore, the correct statements in the context of hereditary diseases are:
1. Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilisation of egg.
This statement is correct as mitochondrial replacement therapy can prevent the transmission of mitochondrial diseases from a mother to her child. It involves replacing the defective mitochondria in the mother's egg or embryo with healthy ones from a donor, thereby preventing the inheritance of the disease.
2. A child inherits mitochondrial diseases entirely from the mother and not from the father.
This statement is also correct as the egg contributes most of the cytoplasmic components, including mitochondria, to the developing embryo. The sperm, on the other hand, only contributes its nucleus, which contains the genetic material. Therefore, mitochondrial diseases are inherited from the mother and not from the father.
In conclusion, both statements are correct in the context of hereditary diseases as mitochondrial replacement therapy can prevent the transmission of mitochondrial diseases from a mother to her child, and mitochondrial diseases are inherited entirely from the mother and not from the father.
In the context of hereditary diseases, consider the following statemen...
Answer to above question is A.
Mitochondrial hereditary diseases can be controlled by In Vitro Fertilization and Replacement of Mitochondrial components. Replacement can be done before or after Invitro Fertilization. They are two methods .
1. Maternal Spindle transfer 2. Pro Nuclear transfer.
As sperm has low number of Mitochondria and mitochondrial genes, hence they are inherited only from mother.
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