How many points are there in the TCA cycle where NAD+is reduced?a)Oneb...
There are three points in the TCA cycle where NAD+ is reduced to NADH + H+ and one point where FAD+ is reduced to FADH2. In a coupled reaction GTP is converted to GDP with the simultaneous synthesis of ATP from ADP.
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How many points are there in the TCA cycle where NAD+is reduced?a)Oneb...
Explanation:
Points in the TCA cycle where NAD+ is reduced:
- The TCA cycle, also known as the citric acid cycle, is a series of chemical reactions that generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.
- NAD+ (nicotinamide adenine dinucleotide) is a coenzyme that plays a crucial role in the TCA cycle by accepting electrons and protons to become NADH.
- There are three points in the TCA cycle where NAD+ is reduced to NADH:
1. Isocitrate Dehydrogenase Reaction: In this step, isocitrate is oxidized to alpha-ketoglutarate, and NAD+ is reduced to NADH.
2. Alpha-Ketoglutarate Dehydrogenase Complex Reaction: Alpha-ketoglutarate is oxidized to succinyl-CoA, and NAD+ is again reduced to NADH.
3. Malate Dehydrogenase Reaction: Malate is oxidized to oxaloacetate, and NAD+ is once more reduced to NADH.
- Therefore, there are a total of three points in the TCA cycle where NAD+ is reduced to NADH. This reduction of NAD+ to NADH is essential for the generation of ATP through oxidative phosphorylation in the electron transport chain.