The European Federation of Biotechnology (EFB) defines biotechnology as the integrated use of biochemistry, microbiology, and chemical engineering to achieve the application of biological systems and organisms for the production of goods and services. The EFB's definition of biotechnology is comprehensive and encompasses both traditional and modern approaches to the field. Specifically, it includes genetic engineering and traditional breeding methods, as well as modern molecular biotechnology techniques.

1. Genetic engineering:
Genetic engineering involves manipulating an organism's genetic material to introduce new traits or modify existing ones. This can be done by directly altering the DNA of an organism using techniques such as recombinant DNA technology, gene cloning, and gene transfer. Genetic engineering allows for the production of genetically modified organisms (GMOs) that have desirable traits, such as increased yield, disease resistance, or improved nutritional content.

2. Traditional breeding:
Traditional breeding refers to the selective breeding of plants and animals to achieve desired traits. This method has been practiced for centuries and involves crossing individuals with desirable characteristics to produce offspring with a combination of those traits. Traditional breeding relies on natural genetic variation within a species and does not involve the direct manipulation of an organism's DNA. It is a slower process compared to genetic engineering but has been highly successful in improving crop yields, developing disease-resistant varieties, and enhancing livestock traits.

3. Modern molecular biotechnology:
Modern molecular biotechnology encompasses a wide range of techniques and approaches that utilize the knowledge of molecular biology to manipulate and study biological systems. This includes techniques such as DNA sequencing, gene expression analysis, protein engineering, and bioprocess optimization. These methods allow scientists to better understand the structure, function, and regulation of genes and proteins, leading to the development of new drugs, diagnostic tools, and biotechnological products.

4. Both traditional and modern molecular biotechnology:
The EFB's definition of biotechnology recognizes that biotechnological advancements are not limited to just one approach. It encompasses both traditional breeding methods that have been used for centuries and modern molecular biotechnology techniques that have revolutionized the field. By including both approaches, the EFB acknowledges the importance of building upon the knowledge and successes of traditional methods while embracing the potential of modern molecular techniques to further enhance biotechnological applications.

In conclusion, the EFB's definition of biotechnology encompasses a broad range of approaches, including genetic engineering, traditional breeding, and modern molecular biotechnology. This comprehensive definition recognizes the diverse methods and techniques that contribute to the field and highlights the potential for innovation and advancement in biotechnological applications.