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Which of the following is performed by coenzyme A?
  • a)
    Oxidative phosphorylation
  • b)
    Substrate level phosphorylation
  • c)
    Breakdown of pyruvate
  • d)
    Activation of acetyl group
Correct answer is option 'D'. Can you explain this answer?
Most Upvoted Answer
Which of the following is performed by coenzyme A?a)Oxidative phosphor...
CoA is acetylated to acetyl CoA by the breakdown of carbohydrates through glycolysis and by the breakdown of fatty acids through β-oxidation.
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Which of the following is performed by coenzyme A?a)Oxidative phosphor...
Activation of acetyl group
Coenzyme A plays a crucial role in the activation of acetyl groups, which is an essential step in various metabolic processes.

Formation of Acetyl-CoA
Coenzyme A binds to the acetyl group derived from pyruvate or fatty acids to form acetyl-CoA. This process is catalyzed by the enzyme pyruvate dehydrogenase in the case of pyruvate breakdown.

Role in Citric Acid Cycle
Acetyl-CoA is a key molecule in the citric acid cycle. It enters the cycle and undergoes a series of reactions to produce energy in the form of ATP. Coenzyme A facilitates the transfer of acetyl groups within the cycle.

Role in Fatty Acid Synthesis
In fatty acid synthesis, acetyl-CoA serves as a precursor for the synthesis of fatty acids. Coenzyme A is required for the activation of acetyl groups before they can be used in the fatty acid synthesis pathway.

Regulation of Metabolism
Coenzyme A is involved in regulating the balance of metabolic pathways by controlling the availability of acetyl groups. It acts as a carrier of acetyl units and facilitates their transfer between different metabolic reactions.
In summary, coenzyme A plays a crucial role in the activation of acetyl groups, which are essential for various metabolic processes including the breakdown of pyruvate, the citric acid cycle, and fatty acid synthesis.
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Which of the following is performed by coenzyme A?a)Oxidative phosphorylationb)Substrate level phosphorylationc)Breakdown of pyruvated)Activation of acetyl groupCorrect answer is option 'D'. Can you explain this answer?
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