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Which of the following is performed by coenzyme A?
  • a)
    Oxidative phosphorylation
  • b)
    Substrate level phosphorylation
  • c)
    Breakdown of pyruvate
  • d)
    Activation of acetyl group
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
Which of the following is performed by coenzyme A?a)Oxidative phosphor...
CoA is acetylated to acetyl CoA by the breakdown of carbohydrates through glycolysis and by the breakdown of fatty acids through β-oxidation.
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Which of the following is performed by coenzyme A?a)Oxidative phosphor...
Activation of acetyl group
Coenzyme A plays a crucial role in the activation of acetyl groups, which is an essential step in various metabolic processes.

Formation of Acetyl-CoA
Coenzyme A binds to the acetyl group derived from pyruvate or fatty acids to form acetyl-CoA. This process is catalyzed by the enzyme pyruvate dehydrogenase in the case of pyruvate breakdown.

Role in Citric Acid Cycle
Acetyl-CoA is a key molecule in the citric acid cycle. It enters the cycle and undergoes a series of reactions to produce energy in the form of ATP. Coenzyme A facilitates the transfer of acetyl groups within the cycle.

Role in Fatty Acid Synthesis
In fatty acid synthesis, acetyl-CoA serves as a precursor for the synthesis of fatty acids. Coenzyme A is required for the activation of acetyl groups before they can be used in the fatty acid synthesis pathway.

Regulation of Metabolism
Coenzyme A is involved in regulating the balance of metabolic pathways by controlling the availability of acetyl groups. It acts as a carrier of acetyl units and facilitates their transfer between different metabolic reactions.
In summary, coenzyme A plays a crucial role in the activation of acetyl groups, which are essential for various metabolic processes including the breakdown of pyruvate, the citric acid cycle, and fatty acid synthesis.
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Read the passage given below and answer the following questions:Adenosine triphosphate (ATP) is the energy carrying molecule found in the cells of all living things. ATP captures chemical energy obtained from the breakdown of food molecules and releases it to fuel other cellular processes. ATP is a nucleotide that consists of three main structures: the nitrogenous base, adenine; the sugar, ribose; and a chain of three phosphate groups bound to ribose. The phosphate tail of ATP is the actual power source which the cell taps. Available energy is contained in the bonds between the phosphates and is released when they are broken, which occurs through the addition of a water molecule (a process called hydrolysis). Usually only the outer phosphate is removed from ATP to yield energy; when this occurs ATP is converted to adenosine diphosphate (ADP), the form of the nucleotide having only two phosphates.The importance of ATP (adenosine triphosphat e) as the main source of chemical energy in living matter and its involvement in cellular processes has long been recognized. The primary mechanism whereby higher organisms, including humans, generate ATP is through mitochondrial oxidative phosphorylation. For the majority of organs, the main metabolic fuel is glucose, which in the presence of oxygen undergoes complete combustion to CO2 and H2O: C6H12O6 + 6O2 → 6O2 + 6H2O + energyThe free energy (ΔG) liberated in this exergonic (ΔG is negative) reaction is partially trapped as ATP in two consecutive processes: glycolysis (cytosol) and oxidative phosphorylation (mitochondri

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Which of the following is performed by coenzyme A?a)Oxidative phosphorylationb)Substrate level phosphorylationc)Breakdown of pyruvated)Activation of acetyl groupCorrect answer is option 'D'. Can you explain this answer?
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