Can you explain the answer of this question below:A pregnant lady had ...
Caught during pregnancy, toxoplasmosis can cause miscarriage, stillbirth or damage to the baby's brain and other organs, particularly the eyes. However, most babies born with toxoplasmosis have no obvious damage at birth but develop symptoms, usually eye damage, during childhood or even adulthood.
Can you explain the answer of this question below:A pregnant lady had ...
Understanding the Case
A pregnant woman presented with mild cervical lymphadenopathy during her first trimester, which is often indicative of an infectious process. The absence of significant complaints might suggest a subtle infection.
The Prescription and Non-compliance
She was prescribed spiramycin, an antibiotic commonly used to treat toxoplasmosis. However, her non-compliance with the medication could have allowed the infection to progress unnoticed.
Consequences for the Baby
The baby was born with hydrocephalus and intracerebral calcifications, which are significant findings that suggest a congenital infection.
Likely Cause: Toxoplasmosis
- Toxoplasmosis is caused by the parasite Toxoplasma gondii, which can be transmitted from mother to fetus during pregnancy.
- It often presents with mild symptoms in the mother, such as lymphadenopathy.
- Congenital toxoplasmosis is associated with severe outcomes, including:
- Hydrocephalus
- Intracerebral calcifications
- Vision problems and other neurological deficits
Other Options Considered
- Cytomegalovirus (CMV): While it can cause similar symptoms, it typically presents with a different clinical picture and is less commonly associated with isolated lymphadenopathy in the mother.
- Cryptococcus: This is primarily related to immunocompromised individuals and does not typically cause congenital infections.
- Rubella: Although it can lead to congenital defects, the specific findings in this case are more characteristic of toxoplasmosis.
Conclusion
Given the clinical presentation and the outcomes observed in the infant, the most likely cause of the congenital issues is A: Toxoplasmosis.