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Consider the following statements regarding the Edwards syndrome:
1. It is an autosomal chromosomal disorder due to an extra copy of chromosome 18. 
2. It affects child’s body development and growth.
Which of the statements given above is/are correct?
  • a)
    1 only
  • b)
    2 only
  • c)
    Both 1 and 2
  • d)
    Neither 1 nor 2
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
Consider the following statements regarding the Edwards syndrome:1. It...
Researchers have reported chromosomal disorders discovered from prehistoric skeletal remains, dating up to approximately 5,500 years old — including six cases of Down syndrome and one case of Edwards syndrome.
  • It is also known as trisomy 18.
  • It is an autosomal chromosomal disorder due to an extra copy of chromosome 18. 
  • It is a very severe genetic condition that affects child’s body development and growth.
  • Symptoms: Children diagnosed with trisomy 18 have a low birth weight, multiple birth defects and defining physical characteristics.
  • There are three types of Edwards syndrome
  • Complete trisomy 18:
  • It is the most common form (94%).
  • In this type, every cell contains three complete copies of chromosome 18.
  • The extra chromosome is most often of maternal origin.
  • Mosaic trisomy 18:
  • It is the second most common type (less than 5%).
  • In this type, both a complete trisomy 18 and a normal cell line exist.
  • Partial trisomy 18:
  • In this type, only a partial segment of chromosome 18 is present in triplicate.
  • The partial triplicate often results from a balanced translocation or inversion carried by one of the parents.
  • Treatment: There are no specific treatments for trisomy 18. Treatment will focus on the symptoms of the condition, such as heart conditions, breathing difficulties and infections.
Hence both statements are correct.
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