Which of the following is not a function of the Sertoli cells in the m...
Answer: Option B: Secrete testosterone
Solution: Sertoli cells provide nutrition to spermatogonia, support developing germ cells, and secrete androgen-binding protein (ABP), but they do not secrete testosterone. Testosterone is actually secreted by the Leydig cells (interstitial cells) located in the interstitial spaces between the seminiferous tubules. An additional fact about Sertoli cells is that they also play a key role in the blood-testis barrier, protecting germ cells from autoimmune attacks.
View all questions of this test
Which of the following is not a function of the Sertoli cells in the m...
Understanding Sertoli Cells
Sertoli cells, located in the seminiferous tubules of the testes, play essential roles in male reproductive physiology. They are often referred to as "nurse cells" because they provide support and nourishment to developing sperm cells.
Functions of Sertoli Cells
- Provide Nutrition to Spermatogonia: Sertoli cells supply nutrients and biochemical support to spermatogonia and developing spermatozoa, facilitating their growth and maturation.
- Support Developing Germ Cells: They create a protective environment for germ cells, ensuring proper development and differentiation into mature sperm.
- Secrete Androgen-Binding Protein (ABP): Sertoli cells produce ABP, which binds testosterone and keeps its levels high in the seminiferous tubules, promoting spermatogenesis.
Why Option B is Correct
- Secretion of Testosterone: Sertoli cells do not secrete testosterone. This function is primarily performed by Leydig cells, which are located in the interstitial space of the testes. Leydig cells respond to luteinizing hormone (LH) and are responsible for the production of testosterone, which is crucial for male secondary sexual characteristics and overall reproductive health.
Conclusion
In summary, while Sertoli cells have vital supportive and regulatory roles in spermatogenesis, they are not involved in the secretion of testosterone. This vital function is attributed to Leydig cells, making option B the correct choice in this context.