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Consider the following statements regarding Thrombosis with Thrombocytopenia Syndrome:
1. It is characterized by blood clots combined with low levels of platelets in human body.
2. It is more common among younger age groups.
Which of the statements given above is/are correct?
  • a)
    1 only
  • b)
    2 only
  • c)
    Both 1 and 2
  • d)
    Neither 1 nor 2
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
Consider the following statements regarding Thrombosis with Thrombocyt...
Recently, AstraZeneca (AZ) has admitted its Covid vaccine may cause Thrombosis with Thrombocytopenia Syndrome (TTS). 
  • It is characterized by blood clots (thrombosis) combined with low levels of platelets (thrombocytopenia), which are necessary for blood clotting.
  • It often involves unusual blood clot locations, such as in the brain (cerebral venous sinus thrombosis) or abdomen.
  • Symptoms of TTS: Severe or persistent headaches, blurred vision, Shortness of breath, Chest pain, Leg swelling, Persistent abdominal pain and Easy bruising or tiny blood spots under the skin beyond the injection site etc.
  • It is classified into two tiers based on the location of the blood clot and the severity of the symptoms.
  • Tier 1:
  • Uncommon site of thrombosis (like the brain-cerebral venous sinus thrombosis or the gut such as splanchnic vein, associated with bowel ischaemia and surgery, portal vein or other rare venous and arterial thromboses)
  • Thrombosis in more common locations (deep vein thrombosis or pulmonary embolism)
  • Platelet count is less than 1,50,000 per microlitre
  • A positive anti-PF4 ELISA result is supportive, but not required for diagnosis.
  • Tier 2:
  • Common sites of thrombosis include leg or lungs (venous thromboembolism, deep vein thrombosis, pulmonary embolism)
  • Platelet count is less than 1,50,000 per microlitre
  • A positive anti-PF4 ELISA result is required.
  • Tier 1 TTS carries a higher risk of mortality and morbidity than Tier 2. Tier 1 could be more common among younger age groups.
Hence both statements are correct.
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Community Answer
Consider the following statements regarding Thrombosis with Thrombocyt...
Thrombosis with Thrombocytopenia Syndrome (TTS):
Thrombosis with Thrombocytopenia Syndrome (TTS) is a rare but serious condition characterized by blood clots combined with low levels of platelets in the human body.

Statement Analysis:

Statement 1: It is characterized by blood clots combined with low levels of platelets in the human body.
- This statement is correct. TTS involves the formation of blood clots in various parts of the body along with a decrease in platelet levels, which are crucial for blood clotting.

Statement 2: It is more common among younger age groups.
- This statement is incorrect. TTS has been reported in individuals of various age groups, and there is no specific age group that is more prone to developing this condition.

Conclusion:
Both statements 1 and 2 have been analyzed, and it is evident that statement 1 is correct while statement 2 is incorrect. Therefore, the correct answer is option C) Both 1 and 2.
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Consider the following statements regarding Thrombosis with Thrombocytopenia Syndrome:1. It is characterized by blood clots combined with low levels of platelets in human body.2. It is more common among younger age groups.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?
Question Description
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